General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 3164 |
Name | NR4A1 |
Synonymous | GFRP1|HMR|N10|NAK-1|NGFIB|NP10|NUR77|TR3;nuclear receptor subfamily 4, group A, member 1;NR4A1;nuclear receptor subfamily 4, group A, member 1 |
Definition | ST-59|TR3 orphan receptor|early response protein NAK1|growth factor-inducible nuclear protein N10|hormone receptor|nerve growth factor IB nuclear receptor variant 1|nuclear hormone receptor NUR/77|nuclear receptor subfamily 4 group A member 1|orphan nucle |
Position | 12q13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
Nur77(h) + MVP(h) <==> Nur77(h):MVP(h) (binding) | Nur77(h) --> CYP11B2(h) (DNA binding; transactivation). | Nur77(h) --> NR3C1(h) (DNA binding). | Nur77(h) --> HSD3B2(h) (DNA binding). | Nur77(h) + ATP --> Nur77(h){pT} + ADP (phosphorylation) | NR4A1(h) --> Nur77(h) (expression). | Substance P(m.s.) --> Nur77(h) (increase of abundance) | Nur77(h) --> E2F1(h) (DNA binding; transactivation) | Nur77(h) --> SERPINE1(h) (DNA binding; transactivation). | Nur77(h) --> ALDOC(h) (DNA binding). | Nur77(h) --> POMC(h) (DNA binding). | NR4A1(h) --> Nur77(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
341 | Phosphoserine (by PKA) (By similarity). | Swiss-Prot 53.0 | 351 | Phosphoserine (by PKA) (By similarity). | Swiss-Prot 53.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr12 |
Promoter: 50729958 - 50731958 | Agilent_014791 |
chr12 |
Promoter: 50722263 - 50724263 | Agilent_014791 |
chr12 |
Promoter: 50729958 - 50731958 | GSE27584 |
chr12 |
Promoter: 50729958 - 50731958 | GSE27584 |