Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3169

Name

FOXA1

Synonymous

HNF3A|TCF3A;forkhead box A1;FOXA1;forkhead box A1

Definition

HNF-3-alpha|HNF-3A|TCF-3A|forkhead box protein A1|hepatocyte nuclear factor 3-alpha|transcription factor 3A

Position

14q21.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

HNF3A(h) --> IGFBP1(h) (DNA binding).
HNF3A(h) --> SFTPD(h) (DNA binding).
HNF3A(h) --> Foxa1(r) (DNA binding; transactivation).
HNF3A(h) + brca1(h) <==> brca1(h):HNF3A(h) (binding)
HNF3A(h) --> CDKN1B(m) (DNA binding; transactivation).
HNF3A(h) --> Ug(rb) (DNA binding; transactivation).
HNF3A(h) --> EPHX1(h) (DNA binding).
HNF3A(h) --> AMBP(h) (DNA binding).
HNF3A(h) --> apoB(h) (DNA binding; transactivation).
HNF3A(h) --> ALB(r) (DNA binding).
HNF3A(h) --> GCG(r) (DNA binding).
HNF3A(h) --> TF(h) (DNA binding).
HNF3A(h) --> TTR(r) (DNA binding).
HNF3A(h) --> MUC4(h) (DNA binding).
HNF3A(h) --> HSPA2(h) (DNA binding; transactivation).
HNF3A(h) --> SP-B(h) (DNA binding).
HNF3A(h) --> BCL2(h) (DNA binding).
HNF3A(h) --> UPK2(h) (DNA binding).
HNF3A(h) --> ELK4(h) (transactivation)
FOXA1(h) --> HNF3A(h) (expression).
HNF3A(h) --> Ug(rb) (DNA binding; transactivation).
HNF3A(h) --> Cyp7a1(r) (DNA binding; transactivation).
HNF3A(h) --> SP-B(rb) (DNA binding; transactivation).
HNF3A(h) --> RP11-49G10.8(h) (DNA binding).
HNF3A(h) --> HSPA2(h) (transactivation)
HNF3A(h) --/ BCL2(h) (transrepression)
FOXA1(h) --> HNF3A(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for FOXA1

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 37133740 - 37135740Agilent_014791

chr14

Promoter: 37133740 - 37135740GSE27584


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