Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3329

Name

HSPD1

Synonymous

CPN60|GROEL|HLD4|HSP-60|HSP60|HSP65|HuCHA60|SPG13;heat shock 60kDa protein 1 (chaperonin);HSPD1;heat shock 60kDa protein 1 (chaperonin)

Definition

60 kDa chaperonin|60 kDa heat shock protein, mitochondrial|P60 lymphocyte protein|chaperonin 60|heat shock protein 65|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1

Position

2q33.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Hsp60(h) + PrPc(gl) <==> Hsp60(h):PrPc(gl) (binding)
proCaspase-3(h) + Hsp10(h) + Hsp60(h) <==> proCaspase-3(h):Hsp10(h):Hsp60(h) (binding)
Hsp60(h) + proCaspase-3(h) <==> Hsp60(h):proCaspase-3(h) (binding)
Hsp60(h) + proCaspase-6(h) <==> Hsp60(h):proCaspase-6(h) (binding)
proCaspase-6(h) + Hsp60(h) + proCaspase-3(h) <==> proCaspase-6(h):Hsp60(h):proCaspase-3(h) (binding)
Hsp60(h) + GR(r) <==> Hsp60(h):GR(r) (binding)
Hsp60(h) + TLR1(h) <==> Hsp60(h):TLR1(h) (binding)
HDAC1(h) + Hsp60(h) <==> HDAC1(h):Hsp60(h) (binding)
Hsp60(h) + Gp78(h) <==> Hsp60(h):Gp78(h) (binding)
HSPD1(h) --> Hsp60(h) (expression).
HSPD1(h) --> Hsp60(h) (expression).
HSPD1(h) --> HSPD1(h) (expression).
hsa-miR-1 --/ HSPD1(h) (translational repression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

70Phosphoserine.Swiss-Prot 53.0
227Phosphotyrosine.Swiss-Prot 53.0
227Phosphotyrosine15592455Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr2

Promoter: 198072385 - 198074385Agilent_014791

chr2

Promoter: 198072743 - 198074743GSE27584

chr2

Promoter: 198072385 - 198074385GSE27584

chr2

Promoter: 198072385 - 198074385Agilent_014791_44K


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