Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3482

Name

IGF2R

Synonymous

CD222|CIMPR|M6P-R|MPR1|MPRI;insulin-like growth factor 2 receptor;IGF2R;insulin-like growth factor 2 receptor

Definition

300 kDa mannose 6-phosphate receptor|CI Man-6-P receptor|CI-MPR|IGF-II receptor|M6P/IGF2 receptor|M6P/IGF2R|M6PR|MPR 300|cation-independent mannose-6 phosphate receptor|cation-independent mannose-6-phosphate receptor|insulin-like growth factor II receptor

Position

6q26

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

IGF2R(h) --> IGF-2R(h) (expression).
IGF2R(h) --> IGF-2R(h) (expression).
hsa-miR-657 --/ IGF-2R(h) (translational repression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

112N-linked (GlcNAc...).Swiss-Prot 53.0
400N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
435N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
543N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
581N-linked (GlcNAc...).Swiss-Prot 53.0
626N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
747N-linked (GlcNAc...).Swiss-Prot 53.0
871N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
951N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
957N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1164N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1246N-linked (GlcNAc...).Swiss-Prot 53.0
1312N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1656N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1757N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1816N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2085N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2136N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
2409Phosphoserine.Swiss-Prot 53.0
2479Phosphoserine.Swiss-Prot 53.0
2484Phosphoserine.Swiss-Prot 53.0
2409Phosphoserine (CK2 alpha)8318012;17081983Phospho.ELM 6.0
2484Phosphoserine (CK2 alpha)8318012;17081983Phospho.ELM 6.0
2479Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr6

Promoter: 160308621 - 160310621Agilent_014791

chr6

Promoter: 160308621 - 160310621GoldenGate_Methylation_Cancer_Panel_I

chr6

Promoter: 160308621 - 160310621GSE27584

chr6

Promoter: 160308621 - 160310621Agilent_014791_44K

chr6

Promoter: 160308621 - 160310621E-GEOD-20553


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