Entrez Gene

Basic Information
Gene ID	3487
Name	IGFBP4
Synonymous	BP-4\|HT29-IGFBP\|IBP4\|IGFBP-4;insulin-like growth factor binding protein 4;IGFBP4;insulin-like growth factor binding protein 4
Definition	IBP-4\|IGF-binding protein 4\|insulin-like growth factor-binding protein 4
Position	17q21.2
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
IGFBP-4(h) + HKII(r) <==> IGFBP-4(h):HKII(r) (binding)
HKIII(r) + IGFBP-4(h) <==> HKIII(r):IGFBP-4(h) (binding)
IGF-1(h) + IGFBP-4(h) <==> IGF-1(h):IGFBP-4(h) (binding)
IGF-2(m.s.) + IGFBP-4(h) <==> IGF-2(m.s.):IGFBP-4(h) (binding)
IGF-2(h) + IGFBP-4(h) <==> IGF-2(h):IGFBP-4(h) (binding)
IGF-2(h) + IGFBP-4(h) <==> IGF-2(h):IGFBP-4(h) (binding)
IGFBP-4(h) --PAPP-A(h)--> protein remnants (cleavage)
IGFBP-4(h) --kallikrein-2(h)--> IGFBP4-p21(h) + protein remnants (cleavage)
IGFBP-4(h) --kallikrein-2(h)--> IGFBP4-p10(h) + protein remnants (cleavage)
IGFBP-4(h) --kallikrein-3(h)--> IGFBP4-p26(h) + protein remnants (cleavage)
IGFBP-4(h) --kallikrein-3(h)--> IGFBP4-p21(h) + protein remnants (cleavage)
TSP-1(h) + IGFBP-4(h) <==> TSP-1(h):IGFBP-4(h) (binding)
IGFBP4(h) --> IGFBP-4(h) (expression).
IGF-2(h) + IGFBP-4(h) <==> IGF-2(h):IGFBP-4(h) (binding)
IGF-1(h) + IGFBP-4(h) <==> IGF-1(h):IGFBP-4(h) (binding)
IGFBP4(h) --> IGFBP-4(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
125	N-linked (GlcNAc...) (Potential).		Swiss-Prot 53.0