| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3490 |
Name | IGFBP7 |
Synonymous | AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF;insulin-like growth factor binding protein 7;IGFBP7;insulin-like growth factor binding protein 7 |
Definition | IGF-binding protein 7|IGFBP-rP1|PGI2-stimulating factor|angiomodulin|insulin-like growth factor-binding protein 7|prostacyclin-stimulating factor|tumor-derived adhesion factor |
Position | 4q12 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
IGFBP-7(h) --> BAF47(h) (increase of abundance) | IGFBP-7(h) --> SMARCB1(h) (transactivation) | IGFBP-7(h) --> ERK(h){pT}{pY} (decrease of phosphorylation) | IGFBP-7(h) --> BNIP3L(h) (increase of abundance) | IGFBP-7(h) --> MEK(h){p} (decrease of phosphorylation) | IGFBP-7(h) --> RKIP(h) (increase of abundance) | IGFBP-7(h) --> BNIP3L(h) (transactivation) | IGFBP-7(h) --> PEA15(h) (transactivation) | IGFBP-7(h) --> MEN1(h) (transactivation) | IGFBP-7(h) --> FBXO31(h) (transactivation) | IGFBP-7(h) --> HSPA9(h) (transactivation) | IGFBP7(h) --> IGFBP-7(h) (expression). | RA --> IGFBP-7(h) (increase of abundance) | IGFBP7(h) --> IGFBP-7(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
171 | N-linked (GlcNAc...) (Probable). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr4 |
Promoter: 57670796 - 57672796 | Agilent_014791 |
chr4 |
Promoter: 57670796 - 57672796 | GoldenGate_Methylation_Cancer_Panel_I |
chr4 |
Promoter: 57670796 - 57672796 | GSE27584 |
chr4 |
Promoter: 57670796 - 57672796 | Agilent_014791_44K |
chr4 |
Promoter: 57670796 - 57672796 | Agilent_014791 |
chr4 |
Promoter: 57670796 - 57672796 | PMID:17334979 |
chr4 |
Promoter: 57670796 - 57672796 | PMID:16367923 |
chr4 |
Promoter: 57670796 - 57672796 | PMID:14633696 |