Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3651

Name

PDX1

Synonymous

GSF|IDX-1|IPF1|IUF1|MODY4|PAGEN1|PDX-1|STF-1;pancreatic and duodenal homeobox 1;PDX1;pancreatic and duodenal homeobox 1

Definition

IPF-1|IUF-1|glucose-sensitive factor|insulin promoter factor 1, homeodomain transcription factor|insulin upstream factor 1|islet/duodenum homeobox-1|pancreas/duodenum homeobox protein 1|pancreatic-duodenal homeobox factor 1|somatostatin transcription fact

Position

13q12.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for PDX1

Transcription Factors   [Top]

Regulation From TransFac database

ipf1(h) --> GCK(r) (DNA binding).
p38alpha(x) --> ipf1(h) (activation; phosphorylation)
ipf1(h) --> ipf1(h) (expression).
ipf1(h) --> INS(h) (DNA binding; transregulation).
ipf1(h) --> Sst(r) (DNA binding; transactivation).
ipf1(h) --> Pdx1(m) (DNA binding).
ipf1(h) --> ins-1(r) (DNA binding).
ipf1(h) + p300(h) <==> ipf1(h):p300(h) (binding)
ipf1(h) --> ipf1(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for PDX1

Methylation Profile   [Top]

Chromosome

Location

Source

chr13

Promoter: 27390657 - 27392657GoldenGate_Methylation_Cancer_Panel_I

chr13

Promoter: 27390657 - 27392657GSE27584

chr13

Promoter: 27390657 - 27392657Agilent_014791_44K

chr13

Promoter: 27390657 - 27392657E-GEOD-20553

chr13

Promoter: 27390657 - 27392657Agilent_014791


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