| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3678 |
Name | ITGA5 |
Synonymous | CD49e|FNRA|VLA-5|VLA5A;integrin, alpha 5 (fibronectin receptor, alpha polypeptide);ITGA5;integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
Definition | CD49 antigen-like family member E|fibronectin receptor subunit alpha|fibronectin receptor, alpha subunit|integrin alpha-5|integrin alpha-F|very late activation protein 5, alpha subunit |
Position | 12q11-q13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
alpha5-integrin(h) + Nischarin(m) <==> alpha5-integrin(h):Nischarin(m) (binding) | IGFBP-2(m.s.) + alpha5-integrin(h) <==> IGFBP-2(m.s.):alpha5-integrin(h) (binding) | alpha5-integrin(h) --> CCND1(h) (transactivation) | Itga5(h) --> alpha5-integrin(h) (expression). | ErbB2(h) + alpha5-integrin(h) <==> ErbB2(h):alpha5-integrin(h) (binding) | alpha5-integrin(h) + ErbB2(h) <==> alpha5-integrin(h):ErbB2(h) (binding) | aup-1-isoformS(h) + alpha5-integrin(h) <==> aup-1-isoformS(h):alpha5-integrin(h) (binding) | Itga5(h) --> alpha5-integrin(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
84 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 182 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 297 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 307 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 316 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 524 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 530 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 593 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 609 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 675 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 712 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 724 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 773 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 868 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr12 |
Promoter: 53098817 - 53100817 | Agilent_014791 |
chr12 |
Promoter: 53098817 - 53100817 | GSE27584 |
chr12 |
Promoter: 53098817 - 53100817 | Agilent_014791_44K |
chr12 |
Promoter: 53098817 - 53100817 | E-GEOD-20553 |