Entrez Gene

Basic Information
Gene ID	387
Name	RHOA
Synonymous	ARH12\|ARHA\|RHO12\|RHOH12;ras homolog family member A;RHOA;ras homolog family member A
Definition	Aplysia ras-related homolog 12\|h12\|oncogene RHO H12\|ras homolog gene family, member A\|rho cDNA clone 12\|small GTP binding protein RhoA\|transforming protein RhoA
Position	3p21.3
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
RhoA(h) + RhoGEF(m) <==> RhoA(h):RhoGEF(m) (binding)
RhoA(h) + RhoGEF(mo) <==> RhoA(h):RhoGEF(mo) (binding)
RhoA(h) + RhoGAP5(m){p} <==> RhoA(h):RhoGAP5(m){p} (binding)
RhoA(h) + RhoGDI-2(h) <==> RhoA(h):RhoGDI-2(h) (binding)
IL-1RI(h) + RhoA(h) <==> IL-1RI(h):RhoA(h) (binding)
RhoA(h) + RhoGDI-1(h) <==> RhoA(h):RhoGDI-1(h) (binding)
RhoA(h) + AKAP13-Lbc(h) <==> RhoA(h):AKAP13-Lbc(h) (binding)
RhoA(h) + AKAP13-Lbc(h) + PKA-RII(h) <==> RhoA(h):AKAP13-Lbc(h):PKA-RII(h) (binding)
RhoA(h) + Kv1.2(m.s.) <==> RhoA(h):Kv1.2(m.s.) (binding)
AKAP13(h) + RhoA(h) <==> AKAP13(h):RhoA(h) (binding)
RhoA(h) + BPGAP1(h) <==> RhoA(h):BPGAP1(h) (binding)
RhoA(h) + RhoGDI(h) <==> RhoA(h):RhoGDI(h) (binding)
BNIP-2(h) + RhoA(h) <==> BNIP-2(h):RhoA(h) (binding)
plk1(h) + RhoA(h) <==> plk1(h):RhoA(h) (binding)
RhoA(h) + RhoGAP1(h) <==> RhoA(h):RhoGAP1(h) (binding)
RHOA(h) --> RhoA(h) (expression).
P2RX7(h) --> RhoA(h) (activation)
Ost(m.s.) --> RhoA(h) (increase of exchange)
arhgef5(h) --> RhoA(h) (increase of exchange)
LAMA5(h) --> RhoA(h) (activation)
VLA-2(h) --> RhoA(h) (activation)
fibronectin(m.s.) --> RhoA(h) (regulation of localization)
alpha5-integrin(m.s.) --> RhoA(h) (regulation of localization)
beta1-integrin(m.s.) --> RhoA(h) (regulation of localization)
RHOA(h) --> RhoA(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
41	ADP-ribosylasparagine (by botulinumtoxin) (Probable).	Swiss-Prot 53.0
190	Cysteine methyl ester.	Swiss-Prot 53.0
190	S-geranylgeranyl cysteine.	Swiss-Prot 53.0