Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3880

Name

KRT19

Synonymous

CK19|K19|K1CS;keratin 19, type I;KRT19;keratin 19, type I

Definition

40-kDa keratin intermediate filament|CK-19|cytokeratin 19|cytokeratin-19|keratin, type I cytoskeletal 19|keratin, type I, 40-kd|keratin-19

Position

17q21.2

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Keratin-19(h) + ATP --> Keratin-19(h){pS} + ADP (phosphorylation)
Keratin-19(h) + n ATP --> Keratin-19(h){pS}n + n ADP (phosphorylation)
FANCG(h) + Keratin-19(h) <==> FANCG(h):Keratin-19(h) (binding)
Cytokeratin-6B(h) + Keratin-19(h) <==> Cytokeratin-6B(h):Keratin-19(h) (binding)
Keratin-15(h) + Keratin-19(h) <==> Keratin-15(h):Keratin-19(h) (binding)
Keratin-19(h) + pcm1(h) <==> Keratin-19(h):pcm1(h) (binding)
Keratin-19(h) + HRS(h) <==> Keratin-19(h):HRS(h) (binding)
Keratin-19(h) + sfi1(h) <==> Keratin-19(h):sfi1(h) (binding)
Keratin-19(h) + abi2(h) <==> Keratin-19(h):abi2(h) (binding)
Keratin-19(h) + depp(h) <==> Keratin-19(h):depp(h) (binding)
Keratin-19(h) + DRR1(h) <==> Keratin-19(h):DRR1(h) (binding)
Keratin-19(h) + ZFML(h) <==> Keratin-19(h):ZFML(h) (binding)
Keratin-19(h) + ushbp1(h) <==> Keratin-19(h):ushbp1(h) (binding)
Keratin-19(h) + dgcr6L(h) <==> Keratin-19(h):dgcr6L(h) (binding)
Keratin-19(h) + exoc8(h) <==> Keratin-19(h):exoc8(h) (binding)
KRT19(h) --> Keratin-19(h) (expression).
Keratin-19(h) + Pinin(h) <==> Keratin-19(h):Pinin(h) (binding)
Laminin(m) + Keratin-19(h) <==> Laminin(m):Keratin-19(h) (binding)
Laminin(h) + Keratin-19(h) <==> Laminin(h):Keratin-19(h) (binding)
Collagen(b) + Keratin-19(h) <==> Collagen(b):Keratin-19(h) (binding)
fibronectin(h) + Keratin-19(h) <==> fibronectin(h):Keratin-19(h) (binding)
Dystrophin(h) + Keratin-19(h) <==> Dystrophin(h):Keratin-19(h) (binding)
Keratin-19(h) + ATP --> Keratin-19(h){pS35} + ADP (phosphorylation)
Dystrophin-4(h) + Keratin-19(h) <==> Dystrophin-4(h):Keratin-19(h) (binding)
KRT19(h) --> Keratin-19(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

9Phosphoserine (By similarity).Swiss-Prot 53.0
13Phosphoserine (By similarity).Swiss-Prot 53.0
35Phosphoserine.Swiss-Prot 53.0
56Phosphoserine (By similarity).Swiss-Prot 53.0
58Phosphoserine (By similarity).Swiss-Prot 53.0
35Phosphoserine10212274;16083285Phospho.ELM 6.0
10Phosphoserine10212274Phospho.ELM 6.0
46Phosphoserine16083285Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr17

Promoter: 36937660 - 36939660Agilent_014791

chr17

Promoter: 36937660 - 36939660GSE27584


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