Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4057

Name

LTF

Synonymous

GIG12|HEL110|HLF2|LF;lactotransferrin;LTF;lactotransferrin

Definition

epididymis luminal protein 110|growth-inhibiting protein 12|kaliocin-1|lactoferricin|lactoferroxin|neutrophil lactoferrin|talalactoferrin

Position

3p21.31

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for LTF

Transcription Factors   [Top]

Regulation From TransFac database

lactoferrin(h) --> MMP1(h) (DNA binding; transactivation).
lactoferrin(h) --> SKP1A(h) (DNA binding; transactivation).
LTF(h) --> lactoferrin(h) (expression).
SGK-1(h) + lactoferrin(h) <==> SGK-1(h):lactoferrin(h) (binding)
LTF(h) --> lactoferrin(h) (expression).
factor H(h) --> lactoferrin(h) (increase of secretion)

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

156N-linked (GlcNAc...).Swiss-Prot 53.0
497N-linked (GlcNAc...).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 46480899 - 46482899Agilent_014791

chr3

Promoter: 46480899 - 46482899GSE27584

chr3

Promoter: 46480899 - 46482899Agilent_014791_44K


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