Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

406

Name

ARNTL

Synonymous

BMAL1|BMAL1c|JAP3|MOP3|PASD3|TIC|bHLHe5;aryl hydrocarbon receptor nuclear translocator-like;ARNTL;aryl hydrocarbon receptor nuclear translocator-like

Definition

ARNT-like protein 1, brain and muscle|PAS domain-containing protein 3|aryl hydrocarbon receptor nuclear translocator-like protein 1|bHLH-PAS protein JAP3|basic-helix-loop-helix-PAS orphan MOP3|basic-helix-loop-helix-PAS protein MOP3|brain and muscle ARNT-

Position

11p15

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Hsp90(h) + BMAL1(h) <==> Hsp90(h):BMAL1(h) (binding).
BMAL1(h) + AhR(h) <==> BMAL1(h):AhR(h) (binding).
MOP4(h) + BMAL1(h) <==> BMAL1(h):MOP4(h) (binding)
BMAL1(h) + HIF-1alpha(h) <==> HIF-1alpha(h):BMAL1(h) (binding)
BMAL1(h) --> SERPINE1(h) (DNA binding; transactivation).
ARNTL(h) --> BMAL1(h) (expression).
BMAL1(h) --> SERPINE1(h) (DNA binding; transactivation).
ARNTL(h) --> BMAL1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

259Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO) (Bysimilarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 13254401 - 13256401Agilent_014791

chr11

Promoter: 13254401 - 13256401GSE27584

chr11

Promoter: 13254401 - 13256401GSE27584

chr11

Promoter: 13254401 - 13256401GSE27584

chr11

Promoter: 13254401 - 13256401Agilent_014791_44K


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