Entrez Gene

Basic Information
Gene ID	4082
Name	MARCKS
Synonymous	80K-L\|MACS\|PKCSL\|PRKCSL;myristoylated alanine-rich protein kinase C substrate;MARCKS;myristoylated alanine-rich protein kinase C substrate
Definition	myristoylated alanine-rich C-kinase substrate\|myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)\|phosphomyristin\|protein kinase C substrate, 80 kDa protein, light chain
Position	6q22.2
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
MARCKS(h) --> MARCKS(h) (expression).
MARCKS(h) + 2 ATP --> MARCKS(h){pS159}{pS163} + 2 ADP (phosphorylation)
MARCKS(h) --> MARCKS(h) (expression).
MARCKS(h) --> MARCKS(h) (expression).
hsa-miR-21 --/ MARCKS(h) (translational repression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
2	N-myristoyl glycine (By similarity).		Swiss-Prot 53.0
46	Phosphoserine.		Swiss-Prot 53.0
77	Phosphoserine.		Swiss-Prot 53.0
81	Phosphoserine.		Swiss-Prot 53.0
101	Phosphoserine.		Swiss-Prot 53.0
118	Phosphoserine (by MAPK) (By similarity).		Swiss-Prot 53.0
135	Phosphoserine (By similarity).		Swiss-Prot 53.0
143	Phosphothreonine.		Swiss-Prot 53.0
145	Phosphoserine.		Swiss-Prot 53.0
147	Phosphoserine (By similarity).		Swiss-Prot 53.0
159	Phosphoserine (by PKC).		Swiss-Prot 53.0
163	Phosphoserine (by PKC).		Swiss-Prot 53.0
167	Phosphoserine (by PKC).		Swiss-Prot 53.0
170	Phosphoserine (by PKC).		Swiss-Prot 53.0
262	Phosphoserine (By similarity).		Swiss-Prot 53.0
158	Phosphoserine (PKC alpha;PK)	91317794;16116087;11162562;17081983	Phospho.ELM 6.0
162	Phosphoserine (PKC alpha;PK)	91317794;16116087;17081983	Phospho.ELM 6.0
25	Phosphoserine	17081983	Phospho.ELM 6.0
26	Phosphoserine	17081983	Phospho.ELM 6.0
28	Phosphoserine	17081983	Phospho.ELM 6.0
45	Phosphoserine	17081983	Phospho.ELM 6.0
100	Phosphoserine	17081983	Phospho.ELM 6.0
127	Phosphoserine	17081983	Phospho.ELM 6.0
134	Phosphoserine	17081983	Phospho.ELM 6.0
142	Phosphothreonine	17081983	Phospho.ELM 6.0
144	Phosphoserine	17081983	Phospho.ELM 6.0
149	Phosphothreonine	17081983	Phospho.ELM 6.0