| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 4221 |
Name | MEN1 |
Synonymous | MEAI|SCG2;multiple endocrine neoplasia I;MEN1;multiple endocrine neoplasia I |
Definition | menin |
Position | 11q13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
NF-kappaB1-p50(m.s.) + menin-isoform2(h) <==> NF-kappaB1-p50(m.s.):menin-isoform2(h) (binding) | p52(m.s.) + menin-isoform2(h) <==> p52(m.s.):menin-isoform2(h) (binding) | RelA-p65(m.s.) + menin-isoform2(h) <==> RelA-p65(m.s.):menin-isoform2(h) (binding) | menin-isoform2(h) + sin3a(m.s.) <==> menin-isoform2(h):sin3a(m.s.) (binding) | menin-isoform2(h) + HDAC1(m.s.) <==> menin-isoform2(h):HDAC1(m.s.) (binding) | HDAC1(m.s.) + sin3a(m.s.) + menin-isoform2(h) <==> HDAC1(m.s.):sin3a(m.s.):menin-isoform2(h) (binding) | hdac2(m.s.) + sin3a(m.s.) + menin-isoform2(h) <==> hdac2(m.s.):sin3a(m.s.):menin-isoform2(h) (binding) | MEN1(h) --> menin-isoform2(h) (expression). | p50(h) + menin(h) <==> p50(h):menin(h) (binding) | RelA-p65(h) + menin(h) <==> RelA-p65(h):menin(h) (binding) | NF-kappaB1-p50(m.s.) + menin(h) <==> NF-kappaB1-p50(m.s.):menin(h) (binding) | p52(m.s.) + menin(h) <==> p52(m.s.):menin(h) (binding) | menin(h) + RelA-p65(m.s.) <==> menin(h):RelA-p65(m.s.) (binding) | menin(h) + reprimo(h) <==> menin(h):reprimo(h) (binding) | ALL1-p180(h) + ALL1-p320(h) + menin(h) + ash2l-isoform2(h) + ash2l-isoform1(h) + BIG3(h) + HCF2(h) + rbbp5(h) <==> ALL1-p180(h):ALL1-p320(h):rbbp5(h):menin(h):HCF2(h):BIG3(h):ash2l-isoform1(h):ash2l-isoform2(h) (binding) | menin(h) + ALL1-p180(h) <==> menin(h):ALL1-p180(h) (binding) | ALL1-p320(h) + menin(h) + ash2l-isoform2(h) + ash2l-isoform1(h) + BIG3(h) + HCF2(h) + HCF1(h) + rbbp5(h) + ALL1-p180(h) <==> ALL1-p320(h):rbbp5(h):HCF1(h):menin(h):HCF2(h):BIG3(h):ash2l-isoform1(h):ash2l-isoform2(h):ALL1-p180(h) (binding) | ALL1-p320(h) + menin(h) <==> ALL1-p320(h):menin(h) (binding) | menin(h) --> HOXA9(h) (transactivation) | MEN1(h) --> menin(h) (expression). | MEN1(h) --> menin-isoform3(h) (expression). | MEN1(h) --> menin-isoform1(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for MEN1 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr11 |
Promoter: 64334264 - 64336264 | Agilent_014791 |
chr11 |
Promoter: 64334111 - 64336111 | Agilent_014791 |
chr11 |
Promoter: 64334289 - 64336289 | Agilent_014791 |
chr11 |
Promoter: 64334264 - 64336264 | GSE27584 |
chr11 |
Promoter: 64334111 - 64336111 | GSE27584 |
chr11 |
Promoter: 64334111 - 64336111 | GSE27584 |
chr11 |
Promoter: 64334289 - 64336289 | GSE27584 |
chr11 |
Promoter: 64334842 - 64336842 | GSE27584 |
chr11 |
Promoter: 64334842 - 64336842 | GSE27584 |
chr11 |
Promoter: 64334264 - 64336264 | GSE27584 |
chr11 |
Promoter: 64334264 - 64336264 | Agilent_014791_44K |
chr11 |
Promoter: 64334842 - 64336842 | Agilent_014791_44K |
chr11 |
Promoter: 64334842 - 64336842 | Agilent_014791_44K |