Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4292

Name

MLH1

Synonymous

COCA2|FCC2|HNPCC|HNPCC2|hMLH1;mutL homolog 1;MLH1;mutL homolog 1

Definition

DNA mismatch repair protein Mlh1|mutL homolog 1, colon cancer, nonpolyposis type 2

Position

3p21.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

MLH1(h) --Caspase-3(h)--> MLH1-p45(h) + MLH1-p40(h) (processing)
MSH2(h) + MLH1(h) <==> MSH2(h):MLH1(h) (binding)
PMS2(h) + MLH1(h) <==> PMS2(h):MLH1(h) (binding)
PMS2(h) + MLH1(h) + MSH2(h) <==> PMS2(h):MLH1(h):MSH2(h) (binding)
BARD1(h) + BRCA2(h) + brca1(h) + Bach1(h) + MLH1(h) + tubulin(h) + CtIP(h) <==> BARD1(h):BRCA2(h):brca1(h):Bach1(h):MLH1(h):tubulin(h):CtIP(h) (binding)
MLH1(h) + TOP2BP1(h) + Bach1(h) + brca1(h) <==> MLH1(h):TOP2BP1(h):Bach1(h):brca1(h) (binding)
RFC4(h) + RFC2(h) + MLH1(h) + MSH2(h) + RECC1(h) + BLM(h) + ATM(h) + brca1(h) + GTBP(h) <==> RFC4(h):RFC2(h):MLH1(h):MSH2(h):RECC1(h):BLM(h):ATM(h):brca1(h):GTBP(h) (binding)
MLH1(h) + RECC1(h) <==> MLH1(h):RECC1(h) (binding)
GTBP(h) + MLH1(h) <==> GTBP(h):MLH1(h) (binding)
BLM(h) + MLH1(h) <==> BLM(h):MLH1(h) (binding)
Rad50(h) + MLH1(h) <==> Rad50(h):MLH1(h) (binding)
ATM(h) + MLH1(h) <==> ATM(h):MLH1(h) (binding)
beta-adaptin 2(h) + MLH1(h) <==> beta-adaptin 2(h):MLH1(h) (binding)
MLH1(h) + ZC3HDC11A(h) <==> MLH1(h):ZC3HDC11A(h) (binding)
MLH1(h) + Rnf37(h) <==> MLH1(h):Rnf37(h) (binding)
MLH1(h) + TRIM29(h) <==> MLH1(h):TRIM29(h) (binding)
MLH1(h) + Willin(h) <==> MLH1(h):Willin(h) (binding)
MLH1(h) --> MLH1(h) (expression).
MLH1(h) --> MLH1(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for MLH1

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

 Promoter: 37008483 - 37010483GoldenGate_Methylation_Cancer_Panel_I

chr3

 Promoter: 37008483 - 37010483GSE27584

chr3

 Promoter: 37008483 - 37010483Agilent_014791_44K

chr3

 Promoter: 37008483 - 37010483Agilent_014791

chr3

 Promoter: 37008483 - 37010483PMID:21426665

chr3

 Promoter: 37008483 - 37010483PMID:21796503

chr3

 Promoter: 37008483 - 37010483PMID:11496321

chr3

 Promoter: 37008483 - 37010483PMID:11306456

chr3

 Promoter: 37008483 - 37010483PMID:12448005

chr3

 Promoter: 37008483 - 37010483PMID:12695555

chr3

 Promoter: 37008483 - 37010483PMID:12692837

chr3

 Promoter: 37008483 - 37010483PMID:11422806

chr3

 Promoter: 37008483 - 37010483PMID:14556664

chr3

 Promoter: 37008483 - 37010483PMID:12746473

chr3

 Promoter: 37008483 - 37010483PMID:11413518

chr3

 Promoter: 37008483 - 37010483PMID:10418831

chr3

 Promoter: 37008483 - 37010483PMID:15616773

chr3

 Promoter: 37008483 - 37010483PMID:12588445

chr3

 Promoter: 37008483 - 37010483PMID:10861474

chr3

 Promoter: 37008483 - 37010483PMID:12763209

chr3

 Promoter: 37008483 - 37010483PMID:16108828

chr3

 Promoter: 37008483 - 37010483PMID:15991278

chr3

 Promoter: 37008483 - 37010483PMID:16475210

chr3

 Promoter: 37008483 - 37010483PMID:11872960

chr3

 Promoter: 37008483 - 37010483PMID:10070967

chr3

 Promoter: 37008483 - 37010483PMID:14742272

chr3

 Promoter: 37008483 - 37010483PMID:11146446

chr3

 Promoter: 37008483 - 37010483PMID:16075282

chr3

 Promoter: 37008483 - 37010483PMID:10495421

chr3

 Promoter: 37008483 - 37010483PMID:12163364

chr3

 Promoter: 37008483 - 37010483PMID:12964042

chr3

 Promoter: 37008483 - 37010483PMID:15831994

chr3

 Promoter: 37008483 - 37010483PMID:11870538

chr3

 Promoter: 37008483 - 37010483PMID:16163424

chr3

 Promoter: 37008483 - 37010483PMID:10585582

chr3

 Promoter: 37008483 - 37010483PMID:12384516

chr3

 Promoter: 37008483 - 37010483PMID:15735977

chr3

 Promoter: 37008483 - 37010483PMID:15069683

chr3

 Promoter: 37008483 - 37010483PMID:15942635

chr3

 Promoter: 37008483 - 37010483PMID:10980110

chr3

 Promoter: 37008483 - 37010483PMID:11140703

chr3

 Promoter: 37008483 - 37010483PMID:14675710

chr3

 Promoter: 37008483 - 37010483PMID:15526363

chr3

 Promoter: 37008483 - 37010483PMID:15386372

chr3

 Promoter: 37008483 - 37010483PMID:17339237

chr3

 Promoter: 37008483 - 37010483PMID:15760919

chr3

 Promoter: 37008483 - 37010483PMID:17183069

chr3

 Promoter: 37008483 - 37010483PMID:15122305

chr3

 Promoter: 37008483 - 37010483PMID:12000733

chr3

 Promoter: 37008483 - 37010483PMID:10987299

chr3

 Promoter: 37008483 - 37010483PMID:15856472

chr3

 Promoter: 37008483 - 37010483PMID:16033773

chr3

 Promoter: 37008483 - 37010483PMID:11341745

chr3

 Promoter: 37008483 - 37010483PMID:16850502

chr3

 Promoter: 37008483 - 37010483PMID:17372756

chr3

 Promoter: 37008483 - 37010483PMID:10468602

chr3

 Promoter: 37008483 - 37010483PMID:12461746

chr3

 Promoter: 37008483 - 37010483PMID:11870540

chr3

 Promoter: 37008483 - 37010483PMID:16436636

chr3

 Promoter: 37008483 - 37010483PMID:16015629

chr3

 Promoter: 37008483 - 37010483PMID:17189406

chr3

 Promoter: 37008483 - 37010483PMID:16820091

chr3

 Promoter: 37008483 - 37010483PMID:12833454

chr3

 Promoter: 37008483 - 37010483PMID:12569385

chr3

 Promoter: 37008483 - 37010483PMID:11601928

chr3

 Promoter: 37008483 - 37010483PMID:15476557

chr3

 Promoter: 37008483 - 37010483PMID:14508843

chr3

 Promoter: 37008483 - 37010483PMID:11729109

chr3

 Promoter: 37008483 - 37010483PMID:17378912

chr3

 Promoter: 37008483 - 37010483PMID:16336454

chr3

 Promoter: 37008483 - 37010483PMID:12004219

chr3

 Promoter: 37008483 - 37010483PMID:17276933

chr3

 Promoter: 37008483 - 37010483PMID:10922385

chr3

 Promoter: 37008483 - 37010483PMID:10793088

chr3

 Promoter: 37008483 - 37010483PMID:12203784

chr3

 Promoter: 37008483 - 37010483PMID:14734469

chr3

 Promoter: 37008483 - 37010483PMID:15294875

chr3

 Promoter: 37008483 - 37010483PMID:10999752

chr3

 Promoter: 37008483 - 37010483PMID:15297202

chr3

 Promoter: 37008483 - 37010483PMID:9811473

chr3

 Promoter: 37008483 - 37010483PMID:12700670

chr3

 Promoter: 37008483 - 37010483PMID:16928264

chr3

 Promoter: 37008483 - 37010483PMID:16701802

chr3

 Promoter: 37008483 - 37010483PMID:16323174

chr3

 Promoter: 37008483 - 37010483PMID:16343186

chr3

 Promoter: 37008483 - 37010483PMID:10072435

chr3

 Promoter: 37008483 - 37010483PMID:12079302

chr3

 Promoter: 37008483 - 37010483PMID:14760069

chr3

 Promoter: 37008483 - 37010483PMID:16557577

chr3

 Promoter: 37008483 - 37010483PMID:12796396

chr3

 Promoter: 37008483 - 37010483PMID:10550333

chr3

 Promoter: 37008483 - 37010483PMID:16303245

chr3

 Promoter: 37008483 - 37010483PMID:16773633

chr3

 Promoter: 37008483 - 37010483PMID:15240532

chr3

 Promoter: 37008483 - 37010483PMID:16532039

chr3

 Promoter: 37008483 - 37010483PMID:10327053

chr3

 Promoter: 37008483 - 37010483PMID:11753956

chr3

 Promoter: 37008483 - 37010483PMID:15328194

chr3

 Promoter: 37008483 - 37010483PMID:12974095

chr3

 Promoter: 37008483 - 37010483PMID:10766168

chr3

 Promoter: 37008483 - 37010483PMID:12584167

chr3

 Promoter: 37008483 - 37010483PMID:14501508

chr3

 Promoter: 37008483 - 37010483PMID:14668721

chr3

 Promoter: 37008483 - 37010483PMID:16256791

chr3

 Promoter: 37008483 - 37010483PMID:16724696

chr3

 Promoter: 37008483 - 37010483PMID:16764763

chr3

 Promoter: 37008483 - 37010483PMID:15498213

chr3

 Promoter: 37008483 - 37010483PMID:15467712

chr3

 Promoter: 37008483 - 37010483PMID:15471559

chr3

 Promoter: 37008483 - 37010483PMID:15915369

chr3

 Promoter: 37008483 - 37010483PMID:12730870

chr3

 Promoter: 37008483 - 37010483PMID:15635575

chr3

 Promoter: 37008483 - 37010483PMID:17219447

chr3

 Promoter: 37008483 - 37010483PMID:16166431

chr3

 Promoter: 37008483 - 37010483PMID:11786399

chr3

 Promoter: 37008483 - 37010483PMID:16858686

chr3

 Promoter: 37008483 - 37010483PMID:15172987

chr3

 Promoter: 37008483 - 37010483PMID:15543763

chr3

 Promoter: 37008483 - 37010483PMID:14527906

chr3

 Promoter: 37008483 - 37010483PMID:16699861

chr3

 Promoter: 37008483 - 37010483PMID:15746058

chr3

 Promoter: 37008483 - 37010483PMID:16983315

chr3

 Promoter: 37008483 - 37010483PMID:16258501

chr3

 Promoter: 37008483 - 37010483PMID:15551306

chr3

 Promoter: 37008483 - 37010483PMID:16242928

chr3

 Promoter: 37008483 - 37010483PMID:12124340

chr3

 Promoter: 37008483 - 37010483PMID:15309527

chr3

 Promoter: 37008483 - 37010483PMID:12632081

chr3

 Promoter: 37008483 - 37010483PMID:12672028

chr3

 Promoter: 37008483 - 37010483PMID:16619216

chr3

 Promoter: 37008483 - 37010483PMID:12841866

chr3

 Promoter: 37008483 - 37010483PMID:16309235

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