| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 4804 |
Name | NGFR |
Synonymous | CD271|Gp80-LNGFR|TNFRSF16|p75(NTR)|p75NTR;nerve growth factor receptor;NGFR;nerve growth factor receptor |
Definition | NGF receptor|TNFR superfamily, member 16|low affinity nerve growth factor receptor|low affinity neurotrophin receptor p75NTR|low-affinity nerve growth factor receptor|p75 ICD|tumor necrosis factor receptor superfamily member 16 |
Position | 17q21-q22 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
caveolin-1(m) + p75NTR(h) <==> caveolin-1(m):p75NTR(h) (binding) | p75NTR(h) --gamma-secretase(h)--> p75NTR-CTF(h) + p75NTR-ICD(h) (processing) | Fas(h) + p75NTR(h) <==> Fas(h):p75NTR(h) (binding) | p75NTR(h) + BDNF(r) <==> p75NTR(h):BDNF(r) (binding) | BDNF(m) + p75NTR(h) <==> BDNF(m):p75NTR(h) (binding) | NGF(r) + p75NTR(h) <==> NGF(r):p75NTR(h) (binding) | NT-3(r) + p75NTR(h) <==> NT-3(r):p75NTR(h) (binding) | NT-5(r) + p75NTR(h) <==> NT-5(r):p75NTR(h) (binding) | TRADD(h) + p75NTR(h) <==> TRADD(h):p75NTR(h) (binding) | TRADD(h) + p75NTR(h) <==> TRADD(h):p75NTR(h) (binding) | p75NTR(h) --> p75NTR-ICD(h) + protein remnants (processing) | p75NTR(h) --> p75NTR-CTF(h) + protein remnants (processing) | p75NTR(h) + CTGF(h) <==> p75NTR(h):CTGF(h) (binding) | NGFR(h) --> p75NTR(h) (expression). | trkA(r) + p75NTR(h) <==> trkA(r):p75NTR(h) (binding) | trkA(r){p} + p75NTR(h) <==> trkA(r){p}:p75NTR(h) (binding) | Necdin(m) + p75NTR(h) <==> Necdin(m):p75NTR(h) (binding) | MAGEG1(m) + p75NTR(h) <==> MAGEG1(m):p75NTR(h) (binding) | SC-1(r) + p75NTR(h) <==> SC-1(r):p75NTR(h) (binding) | p75NTR(h) + RanBPM(m) <==> p75NTR(h):RanBPM(m) (binding) | RanBPM(m) + p75NTR(h) <==> RanBPM(m):p75NTR(h) (binding) | p75NTR(h) + PKAc-beta-isoform5(h) <==> p75NTR(h):PKAc-beta-isoform5(h) (binding) | PKAc-beta(h) + p75NTR(h) <==> PKAc-beta(h):p75NTR(h) (binding) | p75NTR(h) + ATP --PKAc(b)--> p75NTR(h){pS303} + ADP (phosphorylation) | p75NTR(h) + ATP --> p75NTR(h){pS303} + ADP (phosphorylation) | p75NTR(h) + NgR(m.s.) <==> p75NTR(h):NgR(m.s.) (binding) | p75NTR(h) + 14-3-3epsilon(m) + NADE-isoform1(m) <==> p75NTR(h):14-3-3epsilon(m):NADE-isoform1(m) (binding) | p75NTR(h) + RhoA(m.s.) + RhoGDI-1(h) <==> p75NTR(h):RhoA(m.s.):RhoGDI-1(h) (binding) | RhoGDI-1(m) + RhoA(m.s.) + p75NTR(h) <==> RhoGDI-1(m):RhoA(m.s.):p75NTR(h) (binding) | RhoGDI-1(h) + p75NTR(h) <==> RhoGDI-1(h):p75NTR(h) (binding) | p75NTR(h) --> p75NTR-ICD(h) + protein remnants (processing) | p75NTR(h) --> p75NTR-CTF(h) + protein remnants (processing) | p75NTR(h) + GT1b <==> p75NTR(h):GT1b (binding) | p75NTR(h) --TACE(m)--> p75NTR-ECD(h) + protein remnants (cleavage) | NGFR(h) --> p75NTR(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr17 |
Promoter: 44926166 - 44928166 | Agilent_014791 |
chr17 |
Promoter: 44926166 - 44928166 | GoldenGate_Methylation_Cancer_Panel_I |
chr17 |
Promoter: 44926166 - 44928166 | GSE27584 |
chr17 |
Promoter: 44926166 - 44928166 | Agilent_014791_44K |