Entrez Gene

Basic Information
Gene ID	4849
Name	CNOT3
Synonymous	LENG2\|NOT3\|NOT3H;CCR4-NOT transcription complex, subunit 3;CNOT3;CCR4-NOT transcription complex, subunit 3
Definition	CCR4-NOT transcription complex subunit 3\|CCR4-associated factor 3\|NOT3 (negative regulator of transcription 3, yeast) homolog\|leukocyte receptor cluster member 2
Position	19q13.4
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
CNOT3(h) --> CNOT2(h) (binding)
CNOT3(h) + CNOT8(h) <==> CNOT3(h):CNOT8(h) (binding)
Ku70(h) + Ccte(h) + Pds5A(h) + PPIL1(h) + eIF-3gamma(h) + SAFB1(h) + Wapl(h) + Rad21(h) + SMC-3(h) + SMC1(h) + CAPER-alpha(h) + CNOT3(h) + NCoA-5(h) + SIAHBP1(h) + FBP(h) + HYPA(h) + SKIP(h) + SRm300(h) + SRm160(h) + p54nrb/NonO(h) + rbm25(h) + rbm8A(h) + Pinin(h) + Prp19(h) + cdc5L(h) + Snrp116(h) + Prpf8(h) + Sf3b-4(h) + Sf3b-2(h) + hnRNPM(h) + hnRNP-G(h) <==> Ku70(h):Ccte(h):Pds5A(h):PPIL1(h):eIF-3gamma(h):SAFB1(h):Wapl(h):Rad21(h):SMC-3(h):SMC1(h):CAPER-alpha(h):CNOT3(h):NCoA-5(h):SIAHBP1(h):FBP(h):HYPA(h):SKIP(h):SRm300(h):SRm160(h):p54nrb/NonO(h):rbm25(h):rbm8A(h):Pinin(h):Prp19(h):cdc5L(h):Snrp116(h):Prpf8(h):Sf3b-4(h):Sf3b-2(h):hnRNPM(h):hnRNP-G(h) (binding)
CNOT2(h) + CNOT3(h) <==> CNOT2(h):CNOT3(h) (binding)
CNOT3(h) --> CNOT3(h) (expression).
CNOT3(h) --> CNOT3-isoform1(h) (expression).
CNOT3(h) --> CNOT3-isoform2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
299	Phosphoserine.		Swiss-Prot 53.0
299	Phosphoserine	15302935	Phospho.ELM 6.0