Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4899

Name

NRF1

Synonymous

ALPHA-PAL;nuclear respiratory factor 1;NRF1;nuclear respiratory factor 1

Definition

alpha palindromic-binding protein

Position

7q32

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

NRF-1(h) --> COX-VIc-2(r) (DNA binding).
NRF-1(h) --> UQCRB(h) (DNA binding).
NRF-1(h) --> MRP(m) (DNA binding).
NRF-1(h) --> Cycs(r) (DNA binding).
PGC-1(m) + NRF-1(h) <==> PGC-1(m):NRF-1(h) (binding)
NRF-1(h) --> CD47(h) (DNA binding).
NRF-1(h) --> Zfp106(h) (DNA binding; transactivation).
NRF-1(h) --> Fmr1(m) (DNA binding).
NRF-1(h) --> FXR2(h) (DNA binding).
NRF-1(h) --> E2F-6(h) (DNA binding).
NRF-1(h) --> PPAT(h) (DNA binding).
NRF-1(h) --> PAICS(h) (DNA binding).
NRF-1(h) --> CAPNS1(h) (DNA binding; transactivation).
NRF-1(h) --> SDHA(h) (DNA binding).
NRF-1(h) --> TOMM20(h) (DNA binding).
NRF-1(h) --> Cox5b(m) (DNA binding).
NRF-1(h) --> Cox7c(m) (DNA binding).
NRF-1(h) --> Cox5a(m) (DNA binding).
NRF-1(h) --> Cox6c(m) (DNA binding).
NRF-1(h) --> Cox7b(m) (DNA binding).
NRF-1(h) --> Cox8a(m) (DNA binding).
NRF-1(h) --> Cox6a1(m) (DNA binding).
NRF-1(h) --> Cox6b1(m) (DNA binding).
NRF-1(h) --> Cox7a2(m) (DNA binding).
NRF-1(h) --> Cox4nb(m) (DNA binding).
NRF-1(h) --> VSNL1(h) (DNA binding).
NRF-1(h) --> TOMM34(h) (DNA binding).
NRF1(h) --> NRF-1(h) (expression).
NRF-1(h) --> ATPSG(b) (DNA binding).
NRF-1(h) --> EIF2S1(h) (DNA binding)
NRF-1(h) --> TAT(r) (DNA binding).
NRF-1(h) --> TFAM(h) (DNA binding; transactivation).
NRF-1(h) --/ E2F1(h) (DNA binding; transrepression)
NRF-1(h) --> CD47(h) (DNA binding).
NRF-1(h) --> E2F-6(h) (DNA binding).
NRF-1(h) --> PPAT(h) (DNA binding).
NRF-1(h) --> PAICS(h) (DNA binding).
NRF1(h) --> NRF-1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

39Phosphoserine (by CK2).Swiss-Prot 53.0
44Phosphoserine (by CK2).Swiss-Prot 53.0
46Phosphoserine (by CK2).Swiss-Prot 53.0
47Phosphoserine (by CK2).Swiss-Prot 53.0
52Phosphoserine (by CK2).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

 Promoter: 129037291 - 129039291Agilent_014791

chr7

 Promoter: 129037291 - 129039291GSE27584

chr7

 Promoter: 129037291 - 129039291Agilent_014791_44K

chr7

 Promoter: 129037291 - 129039291Agilent_014791

')