| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 51343 |
Name | FZR1 |
Synonymous | CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1;fizzy/cell division cycle 20 related 1 (Drosophila);FZR1;fizzy/cell division cycle 20 related 1 (Drosophila) |
Definition | CDC20-like 1b|CDC20-like protein 1|cdh1/Hct1 homolog|fizzy-related protein homolog |
Position | 19p13.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
cyclinA(h) + Fzr1(h) <==> cyclinA(h):Fzr1(h) (binding) | Fzr1(h) + ATP --cyclinA(h):Cdk2(h)--> Fzr1(h){p} + ADP (phosphorylation) | Fzr1(h) + ATP --cyclinB1(h):Cdk1(h)--> Fzr1(h){p} + ADP (phosphorylation) | Aurora-B(h) + Fzr1(h) <==> Aurora-B(h):Fzr1(h) (binding) | Fzr1(h) + Aurora-B(r) <==> Fzr1(h):Aurora-B(r) (binding) | Fzr1(h) + p300(h) <==> Fzr1(h):p300(h) (binding) | Fzr1(h) + CBP(h) <==> Fzr1(h):CBP(h) (binding) | Fzr1(h) --/ cyclinA(h) (decrease of abundance) | Fzr1(h) + securin(h) <==> Fzr1(h):securin(h) (binding) | Emi1(h) + Fzr1(h) <==> Emi1(h):Fzr1(h) (binding) | APC1(h) + APC11(h) + APC2(h) + APC4(h) + APC5(h) + APC7(h) + Cdc16(h) + Cdc23(h) + Emi1(h) + Fzr1(h) <==> APC1(h):APC2(h):APC4(h):APC5(h):Cdc16(h):APC7(h):Cdc23(h):APC11(h):Fzr1(h):Emi1(h) (binding) | Fzr1(h) + Emi1(h) <==> Fzr1(h):Emi1(h) (binding) | Nlp(h) + Fzr1(h) <==> Nlp(h):Fzr1(h) (binding) | Fzr1(h) + Nlp(h) <==> Fzr1(h):Nlp(h) (binding) | Fzr1(h) + Anillin(h) <==> Fzr1(h):Anillin(h) (binding) | Fzr1(h) + CKAP2(h) <==> Fzr1(h):CKAP2(h) (binding) | TPX2(h) + Fzr1(h) <==> TPX2(h):Fzr1(h) (binding) | Fzr1(h) + APC2(h) <==> Fzr1(h):APC2(h) (binding) | Fzr1(h) + Cdc20(h) <==> Fzr1(h):Cdc20(h) (binding) | cyclosome(h) + Fzr1(h) <==> cyclosome(h):Fzr1(h) (binding) | Cdc27(h) + Fzr1(h) <==> Cdc27(h):Fzr1(h) (binding) | Fzr1(h) + ATP --> Fzr1(h){p} + ADP (phosphorylation) | FZR1(h) --> Fzr1(h) (expression). | Fzr1(h){p} --Cdc14A(h)--> Fzr1(h) + p (dephosphorylation) | FZR1(h) --> Fzr1-isoform1(h) (expression). | FZR1(h) --> Fzr1-isoform2(h) (expression). | FZR1(h) --> Fzr1-isoform3(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
36 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 151 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
There is no record for FZR1 | ||