Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51548

Name

SIRT6

Synonymous

SIR2L6;sirtuin 6;SIRT6;sirtuin 6

Definition

NAD-dependent deacetylase sirtuin-6|NAD-dependent protein deacetylase sirtuin-6|SIR2-like protein 6|regulatory protein SIR2 homolog 6|sir2-related protein type 6|sirtuin type 6

Position

19p13.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for SIRT6

Transcription Factors   [Top]

Regulation From TransFac database

SIRT6(h) --> SIR2L6-isoform1(h) (expression).
elf5(h) + SIR2L6(h) <==> elf5(h):SIR2L6(h) (binding)
SIR2L6(h) + Mi2-alpha(h) <==> SIR2L6(h):Mi2-alpha(h) (binding)
SIR2L6(h) + vimentin(h) <==> SIR2L6(h):vimentin(h) (binding)
SIRT6(h) --> SIR2L6(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for SIRT6

Methylation Profile   [Top]

Chromosome

Location

Source

chr19

Promoter: 4133096 - 4135096Agilent_014791

chr19

Promoter: 4133096 - 4135096GSE27584

chr19

Promoter: 4133096 - 4135096Agilent_014791_44K


')