General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 51548 |
Name | SIRT6 |
Synonymous | SIR2L6;sirtuin 6;SIRT6;sirtuin 6 |
Definition | NAD-dependent deacetylase sirtuin-6|NAD-dependent protein deacetylase sirtuin-6|SIR2-like protein 6|regulatory protein SIR2 homolog 6|sir2-related protein type 6|sirtuin type 6 |
Position | 19p13.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for SIRT6 |
Transcription Factors [Top] |
Regulation From TransFac database |
SIRT6(h) --> SIR2L6-isoform1(h) (expression). | elf5(h) + SIR2L6(h) <==> elf5(h):SIR2L6(h) (binding) | SIR2L6(h) + Mi2-alpha(h) <==> SIR2L6(h):Mi2-alpha(h) (binding) | SIR2L6(h) + vimentin(h) <==> SIR2L6(h):vimentin(h) (binding) | SIRT6(h) --> SIR2L6(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for SIRT6 |
Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
---|---|---|
chr19 |
Promoter: 4133096 - 4135096 | Agilent_014791 |
chr19 |
Promoter: 4133096 - 4135096 | GSE27584 |
chr19 |
Promoter: 4133096 - 4135096 | Agilent_014791_44K |