Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51741

Name

WWOX

Synonymous

D16S432E|EIEE28|FOR|FRA16D|HHCMA56|PRO0128|SCAR12|SDR41C1|WOX1;WW domain containing oxidoreductase;WWOX;WW domain containing oxidoreductase

Definition

WW domain-containing oxidoreductase|WW domain-containing protein WWOX|fragile site FRA16D oxidoreductase|short chain dehydrogenase/reductase family 41C member 1|short chain dehydrogenase/reductase family 41C, member 1

Position

16q23

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for WWOX

Transcription Factors   [Top]

Regulation From TransFac database

JNK1(h) + WOX1(h) <==> JNK1(h):WOX1(h) (binding)
WOX1(h) + p73(h) <==> WOX1(h):p73(h) (binding)
WOX1(h) + p73alpha(h) <==> WOX1(h):p73alpha(h) (binding)
WOX1(h) + p73beta(h) <==> WOX1(h):p73beta(h) (binding)
WOX1(h) + ATP --Src(h)--> WOX1(h){pY33} + ADP (phosphorylation)
WOX1(h) + ErbB4-CTF(h) <==> WOX1(h):ErbB4-CTF(h) (binding)
WWOX(h) --> WOX1(h) (expression).
WWOX(h) --> WOX1-isoform1(h) (expression).
WWOX(h) --> WOX1-isoform2(h) (expression).
WWOX(h) --> WOX1-isoform3(h) (expression).
WWOX(h) --> WOX1-isoform4(h) (expression).
WWOX(h) --> WOX1-isoform5(h) (expression).
WWOX(h) --> WOX1-isoform6(h) (expression).
WWOX(h) --> WOX1-isoform7(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

14Phosphoserine (By similarity).Swiss-Prot 53.0
33Phosphotyrosine.Swiss-Prot 53.0
33Phosphotyrosine12514174Phospho.ELM 6.0
61Phosphotyrosine12514174Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr16

Promoter: 76689552 - 76691552Agilent_014791

chr16

Promoter: 76689552 - 76691552GSE27584

chr16

Promoter: 76689552 - 76691552GSE27584

chr16

Promoter: 76689552 - 76691552GSE27584

chr16

Promoter: 76689552 - 76691552Agilent_014791_44K

chr16

Promoter: 76689552 - 76691552Agilent_014791


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