| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 51741 |
Name | WWOX |
Synonymous | D16S432E|EIEE28|FOR|FRA16D|HHCMA56|PRO0128|SCAR12|SDR41C1|WOX1;WW domain containing oxidoreductase;WWOX;WW domain containing oxidoreductase |
Definition | WW domain-containing oxidoreductase|WW domain-containing protein WWOX|fragile site FRA16D oxidoreductase|short chain dehydrogenase/reductase family 41C member 1|short chain dehydrogenase/reductase family 41C, member 1 |
Position | 16q23 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for WWOX | |||
Transcription Factors [Top] |
Regulation From TransFac database | JNK1(h) + WOX1(h) <==> JNK1(h):WOX1(h) (binding) | WOX1(h) + p73(h) <==> WOX1(h):p73(h) (binding) | WOX1(h) + p73alpha(h) <==> WOX1(h):p73alpha(h) (binding) | WOX1(h) + p73beta(h) <==> WOX1(h):p73beta(h) (binding) | WOX1(h) + ATP --Src(h)--> WOX1(h){pY33} + ADP (phosphorylation) | WOX1(h) + ErbB4-CTF(h) <==> WOX1(h):ErbB4-CTF(h) (binding) | WWOX(h) --> WOX1(h) (expression). | WWOX(h) --> WOX1-isoform1(h) (expression). | WWOX(h) --> WOX1-isoform2(h) (expression). | WWOX(h) --> WOX1-isoform3(h) (expression). | WWOX(h) --> WOX1-isoform4(h) (expression). | WWOX(h) --> WOX1-isoform5(h) (expression). | WWOX(h) --> WOX1-isoform6(h) (expression). | WWOX(h) --> WOX1-isoform7(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 14 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 33 | Phosphotyrosine. | Swiss-Prot 53.0 | 33 | Phosphotyrosine | 12514174 | Phospho.ELM 6.0 | 61 | Phosphotyrosine | 12514174 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr16 |
Promoter: 76689552 - 76691552 | Agilent_014791 |
chr16 |
Promoter: 76689552 - 76691552 | GSE27584 |
chr16 |
Promoter: 76689552 - 76691552 | GSE27584 |
chr16 |
Promoter: 76689552 - 76691552 | GSE27584 |
chr16 |
Promoter: 76689552 - 76691552 | Agilent_014791_44K |
chr16 |
Promoter: 76689552 - 76691552 | Agilent_014791 |