| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5216 |
Name | PFN1 |
Synonymous | ALS18;profilin 1;PFN1;profilin 1 |
Definition | epididymis tissue protein Li 184a|profilin I|profilin-1 |
Position | 17p13.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
profilin1(h) + CRMP1(h) <==> profilin1(h):CRMP1(h) (binding) | profilin1(h) + RG4(h) <==> profilin1(h):RG4(h) (binding) | profilin1(h) + RIF1(h) <==> profilin1(h):RIF1(h) (binding) | profilin1(h) + Gephyrin(r) <==> profilin1(h):Gephyrin(r) (binding) | PFN1(h) --> profilin1(h) (expression). | profilin1(h) + Gephyrin(r) <==> profilin1(h):Gephyrin(r) (binding) | profilin1(h) + drebrin-isoformA(r) <==> profilin1(h):drebrin-isoformA(r) (binding) | profilin1(h) + Mena(r) <==> profilin1(h):Mena(r) (binding) | profilin1(h) + drebrin(r) <==> profilin1(h):drebrin(r) (binding) | profilin1(h) + Gephyrin(r) <==> profilin1(h):Gephyrin(r) (binding) | PFN1(h) --> profilin1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
2 | N-acetylalanine. | Swiss-Prot 53.0 | 105 | N6-acetyllysine. | Swiss-Prot 53.0 | 129 | Phosphotyrosine. | Swiss-Prot 53.0 | 128 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr17 |
Promoter: 4792070 - 4794070 | GSE27584 |
chr17 |
Promoter: 4792070 - 4794070 | Agilent_014791_44K |