Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5245

Name

PHB

Synonymous

HEL-215|HEL-S-54e|PHB1;prohibitin;PHB;prohibitin

Definition

epididymis luminal protein 215|epididymis secretory sperm binding protein Li 54e

Position

17q21

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

PHB(h) --> Phb(h) (expression).
p53(h) + Phb(h) <==> p53(h):Phb(h) (binding)
Phb(h) + MGMT(h) <==> Phb(h):MGMT(h) (binding)
PHB(h) --> Phb(h) (expression).
PHB(h) --> PHB(h) (expression).
hsa-miR-27a --/ PHB(h) (increase of mRNA decay).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

252Phosphoserine.Swiss-Prot 53.0
254Phosphoserine.Swiss-Prot 53.0
252Phosphoserine17081983Phospho.ELM 6.0
254Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for PHB



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