Entrez Gene

Basic Information
Gene ID	55615
Name	PRR5
Synonymous	FLJ20185k\|PP610\|PROTOR-1\|PROTOR1;proline rich 5 (renal);PRR5;proline rich 5 (renal)
Definition	Rho GTPase activating protein 8\|proline-rich protein 5\|protein observed with Rictor-1
Position	22q13
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
mTOR(h) + Protor-1-isoform1(h) <==> mTOR(h):Protor-1-isoform1(h) (binding)
Protor-1-isoform1(h) + rictor(h) <==> Protor-1-isoform1(h):rictor(h) (binding)
PRR5(h) --> Protor-1-isoform1(h) (expression).
Protor-1(h) + mTOR(h) <==> Protor-1(h):mTOR(h) (binding)
mTOR(h) + Protor-1(h) + rictor(h) <==> mTOR(h):Protor-1(h):rictor(h) (binding)
Protor-1(h) + mTOR(h) + rictor(m.s.) <==> Protor-1(h):mTOR(h):rictor(m.s.) (binding)
Protor-1(h) + rictor(h) <==> Protor-1(h):rictor(h) (binding)
Protor-1(h) + rictor(m.s.) <==> Protor-1(h):rictor(m.s.) (binding)
Protor-1(h) --> p70S6K1(h){pT389} (increase of phosphorylation)
Protor-1(h) --> 4E-BP1(h){pT} (increase of phosphorylation)
Protor-1(h) --> PDGFRbeta(h) (increase of abundance)
Protor-1(h) --> PDGFRB(h) (transactivation)
mTOR(h) + rictor(h) + mLST8(h) + SIN1(h) + Protor-1(h) <==> mTOR(h):rictor(h):mLST8(h):SIN1(h):Protor-1(h) (binding)
PRR5(h) --> Protor-1(h) (expression).
PRR5(h) --> Protor-1-isoform2(h) (expression).
Protor-1-isoform3(h) + mTOR(h) <==> Protor-1-isoform3(h):mTOR(h) (binding)
Protor-1-isoform3(h) + rictor(h) <==> rictor(h):Protor-1-isoform3(h) (binding)
PRR5(h) --> Protor-1-isoform3(h) (expression).
PRR5(h) --> Protor-1-isoform4(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for PRR5