Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

56999

Name

ADAMTS9

Synonymous

-;ADAM metallopeptidase with thrombospondin type 1 motif, 9;ADAMTS9;ADAM metallopeptidase with thrombospondin type 1 motif, 9

Definition

A disintegrin and metalloproteinase with thrombospondin motifs 9|ADAM-TS 9|ADAM-TS9|ADAMTS-9|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9

Position

3p14.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ADAMTS-9-isoform1(h) --> ADAMTS-9-isoform1(h) (translocation)
ADAMTS-9-isoform1(h) + NDP-Gly --> ADAMTS-9-isoform1(h){glyN} + NMP (glycosylation)
ADAMTS-9-isoform1(h) --> ADAMTS-9-isoform1-p28(h) + protein remnants (cleavage)
ADAMTS9(h) --> ADAMTS-9-isoform1(h) (expression).
ADAMTS-9-isoform1(h) --> ADAMTS-9-isoform1(h) (translocation)
versican-V1(h) --ADAMTS-9-isoform1(h)--> versican-V1-p70(h) + protein remnants (cleavage)
AGC1(h) --ADAMTS-9-isoform1(h)--> AGC1-p100(h) + protein remnants (cleavage)
ADAMTS9(h) --> ADAMTS-9-isoform2(h) (expression).
ADAMTS9(h) --> ADAMTS-9-isoform3(h) (expression).
ADAMTS9(h) --> ADAMTS-9(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

112N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
135N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
271N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
749N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
840N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1213N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1267N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1788N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1806N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 64647905 - 64649905Agilent_014791

chr3

Promoter: 64647905 - 64649905GSE27584

chr3

Promoter: 64647905 - 64649905Agilent_014791_44K


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