General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
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Gene ID | 57447 |
Name | NDRG2 |
Synonymous | SYLD;NDRG family member 2;NDRG2;NDRG family member 2 |
Definition | N-myc downstream regulator 2|N-myc downstream-regulated gene 2 protein|NDR1-related protein NDR2|cytoplasmic protein Ndr1|protein NDRG2|syld709613 protein |
Position | 14q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
NDRG2-isoform1(h) + 3 ATP --SGK-1(m.s.)--> NDRG2-isoform1(h){pT330}{pS332}{pT348} + 3 ADP (phosphorylation) | NDRG2-isoform1(h) + 2 ATP --RSK1(m.s.)--> NDRG2-isoform1(h){pS332}{pS350} + 2 ADP (phosphorylation) | NDRG2-isoform1(h) + 2 ATP --p70S6K1(m.s.)--> NDRG2-isoform1(h){pS332}{pS350} + 2 ADP (phosphorylation) | NDRG2-isoform1(h) + 2 ATP --AKT-1(m.s.)--> NDRG2-isoform1(h){pS332}{pT348} + 2 ADP (phosphorylation) | NDRG2(h) --> NDRG2-isoform1(h) (expression). | NDRG2(h) --> NDRG2(h) (expression). | NDRG2(h) --> NDRG2-isoform2(h) (expression). | NDRG2(h) --> NDRG2-isoform3(h) (expression). | NDRG2(h) --> NDRG2-isoform4(h) (expression). | NDRG2(h) --> NDRG2-isoform5(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
328 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 330 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 332 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 334 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 335 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 338 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 344 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 348 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 350 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 352 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 353 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 355 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 357 | Phosphothreonine (By similarity). | Swiss-Prot 53.0 | 350 | Phosphoserine | 15461589 | Phospho.ELM 6.0 | 346 | Phosphoserine | 15461589 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
---|---|---|
chr14 |
Promoter: 20562604 - 20564604 | Agilent_014791 |
chr14 |
Promoter: 20562604 - 20564604 | GSE27584 |
chr14 |
Promoter: 20562604 - 20564604 | GSE27584 |
chr14 |
Promoter: 20563275 - 20565275 | GSE27584 |
chr14 |
Promoter: 20563275 - 20565275 | GSE27584 |
chr14 |
Promoter: 20563275 - 20565275 | GSE27584 |
chr14 |
Promoter: 20562604 - 20564604 | GSE27584 |
chr14 |
Promoter: 20562604 - 20564604 | GSE27584 |
chr14 |
Promoter: 20563275 - 20565275 | GSE27584 |