| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5771 |
Name | PTPN2 |
Synonymous | PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP;protein tyrosine phosphatase, non-receptor type 2;PTPN2;protein tyrosine phosphatase, non-receptor type 2 |
Definition | T-cell protein tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 2 |
Position | 18p11.3-p11.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for PTPN2 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
TC-PTPb(h) + importin-beta1(h) <==> TC-PTPb(h):importin-beta1(h) (binding) | PTPN2(h) --> TC-PTPb(h) (expression). | TC-PTPa(h) + importin-beta1(h) <==> TC-PTPa(h):importin-beta1(h) (binding) | PTPN2(h) --> TC-PTPa(h) (expression). | Shc-1-p52(h){p} --TC-PTPa(h)--> Shc-1-p52(h) + p (dephosphorylation) | 14-3-3sigma(m.s.) + TC-PTP(h) <==> 14-3-3sigma(m.s.):TC-PTP(h) (binding) | PTPN2(h) --> TC-PTP(h) (expression). | STAT1(h){pY701} --TC-PTP(h)--> STAT1(h) + p (dephosphorylation) |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for PTPN2 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr18 |
Promoter: 12873834 - 12875834 | Agilent_014791 |
chr18 |
Promoter: 12873834 - 12875834 | GSE27584 |
chr18 |
Promoter: 12873834 - 12875834 | GSE27584 |
chr18 |
Promoter: 12873834 - 12875834 | GSE27584 |
chr18 |
Promoter: 12873834 - 12875834 | Agilent_014791_44K |