Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5795

Name

PTPRJ

Synonymous

CD148|DEP1|HPTPeta|R-PTP-ETA|SCC1;protein tyrosine phosphatase, receptor type, J;PTPRJ;protein tyrosine phosphatase, receptor type, J

Definition

CD148 antigen|DEP-1|HPTP eta|R-PTP-J|density-enhanced phosphatase 1|human density enhanced phosphatase-1|protein tyrosine phosphatase, receptor type, J polypeptide|protein-tyrosine phosphatase eta|protein-tyrosine phosphatase receptor type J|receptor-type

Position

11p11.2

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

CD148(h) + PDGFRbeta(h){p} <==> CD148(h):PDGFRbeta(h){p} (binding)
CD148(h) --> ECP(h) (activation)
CD148(h) --> EPX(h) (activation)
UV --/ CD148(h) (inhibition)
PTPRJ(h) --> CD148(h) (expression).
ZAP-70(h){p} --CD148(h)--> ZAP-70(h) + p (dephosphorylation)
PLCgamma1(h){p} --CD148(h)--> PLCgamma1(h) + p (dephosphorylation)
LAT(h){p} --CD148(h)--> LAT(h) + p (dephosphorylation)
PTPRJ(h) --> CD148(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

72N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
82N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
93N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
104N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
142N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
172N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
192N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
231N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
258N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
278N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
342N-linked (GlcNAc...).Swiss-Prot 53.0
351N-linked (GlcNAc...).Swiss-Prot 53.0
376N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
391N-linked (GlcNAc...).Swiss-Prot 53.0
396N-linked (GlcNAc...).Swiss-Prot 53.0
413N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
431N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
501N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
525N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
536N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
582N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
603N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
618N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
628N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
637N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
666N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
669N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
761N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
772N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
784N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
790N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
824N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
910N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
937N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 47957189 - 47959189Agilent_014791

chr11

Promoter: 47957189 - 47959189GSE27584

chr11

Promoter: 47957189 - 47959189Agilent_014791_44K


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