| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 580 |
Name | BARD1 |
Synonymous | -;BRCA1 associated RING domain 1;BARD1;BRCA1 associated RING domain 1 |
Definition | BRCA1-associated RING domain gene 1|BRCA1-associated RING domain protein 1 |
Position | 2q35 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
BARD1(h) + brca1(h) <==> BARD1(h):brca1(h) (binding) | BARD1(h) --> BARD1(h) (translocation) | BARD1(h) --> protein remnants (cleavage) | BARD1(h) + DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(h) <==> BARD1(h):DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(h) (binding) | BARD1(h) + nucleophosmin(h) <==> BARD1(h):nucleophosmin(h) (binding) | BRCA2(h) + BARD1(h) + brca1(h) <==> BRCA2(h):BARD1(h):brca1(h) (binding) | BARD1(h) + brca1(h) <==> BARD1(h):brca1(h) (binding) | brca1(m.s.) + BARD1(h) <==> brca1(m.s.):BARD1(h) (binding) | BARD1(h) + Bach1(h) + brca1(h) + BRCA2(h) <==> BARD1(h):Bach1(h):brca1(h):BRCA2(h) (binding) | BARD1(h) + BRCA2(h) + brca1(h) + BRCC36(m.s.) + BRE(h) <==> BARD1(h):BRCA2(h):brca1(h):BRCC36(m.s.):BRE(h) (binding) | BARD1(h) --> p53(h){pS15} (increase of phosphorylation) | BARD1(h) --> BARD1(h) (expression). | BARD1(h) --> BARD1(h) (translocation) | CA150(h) + BARD1(h) <==> CA150(h):BARD1(h) (binding) | BARD1(h) + MYST2(h) <==> BARD1(h):MYST2(h) (binding) | Mi2-alpha(h) + BARD1(h) <==> Mi2-alpha(h):BARD1(h) (binding) | BARD1(h) + IKAP(h) <==> BARD1(h):IKAP(h) (binding) | BARD1(h) + BRD7(h) <==> BARD1(h):BRD7(h) (binding) | BARD1(h) + PIASy(h) <==> BARD1(h):PIASy(h) (binding) | BARD1(h) + Tip60(h) <==> BARD1(h):Tip60(h) (binding) | BARD1(h) + ESET(h) <==> BARD1(h):ESET(h) (binding) | BARD1(h) + zhx1(h) <==> BARD1(h):zhx1(h) (binding) | BARD1(h) + PTN(h) <==> BARD1(h):PTN(h) (binding) | BARD1(h) + FEZ1(h) <==> BARD1(h):FEZ1(h) (binding) | BARD1(h) + Cat-1(h) <==> BARD1(h):Cat-1(h) (binding) | Cat-1-isoform1(h) + BARD1(h) <==> Cat-1-isoform1(h):BARD1(h) (binding) | MYST2(h) + BARD1(h) <==> MYST2(h):BARD1(h) (binding) | CA150(h) + BARD1(h) <==> CA150(h):BARD1(h) (binding) | Mi2alpha-isoform1(h) + BARD1(h) <==> Mi2alpha-isoform1(h):BARD1(h) (binding) | BARD1(h) --> BARD1(h) (translocation) | BARD1(h) + DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(h) <==> BARD1(h):DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(h) (binding) | BARD1(h) + n ATP --Cdk2(m.s.):cyclinE1(h)--> BARD1(h){p}n + n ADP (phosphorylation) | BARD1(h) + ATP --cyclinA1(m.s.):Cdk2(m.s.)--> BARD1(h){p}n + ADP (phosphorylation) | BARD1(h) + ATP --Cdk1(m.s.):cyclinB1(h)--> BARD1(h){p}n + ADP (phosphorylation) | BARD1(h) + BRCA2(h) + brca1(h) + Bach1(h) + MLH1(h) + tubulin(h) + CtIP(h) <==> BARD1(h):BRCA2(h):brca1(h):Bach1(h):MLH1(h):tubulin(h):CtIP(h) (binding) | Rad50(h) + TOP2BP1(h) + brca1(h) + BARD1(h) <==> Rad50(h):TOP2BP1(h):brca1(h):BARD1(h) (binding) | BARD1(h) + NBS1(h) + TOP2BP1(h) + brca1(h) <==> BARD1(h):NBS1(h):TOP2BP1(h):brca1(h) (binding) | Mre11(h) + CtIP(h) + Bach1(h) + Rad50(h) + BARD1(h) <==> Mre11(h):CtIP(h):Bach1(h):Rad50(h):BARD1(h) (binding) | Mre11(h) + NBS1(h) + Bach1(h) + Rad50(h) + TOP2BP1(h) + BARD1(h) <==> Mre11(h):NBS1(h):Bach1(h):Rad50(h):TOP2BP1(h):BARD1(h) (binding) | brca1(h) + BARD1(h) <==> brca1(h):BARD1(h) (binding) | TOP2BP1(h) + BARD1(h) <==> TOP2BP1(h):BARD1(h) (binding) | Rad50(h) + BARD1(h) <==> Rad50(h):BARD1(h) (binding) | BARD1(h) + Mre11(h) <==> BARD1(h):Mre11(h) (binding) | Bach1(h) + TOP2BP1(h) + brca1(h) + BARD1(h) <==> Bach1(h):TOP2BP1(h):brca1(h):BARD1(h) (binding) | CtIP(h) + Rad50(h) + brca1(h) + BARD1(h) <==> CtIP(h):Rad50(h):brca1(h):BARD1(h) (binding) | BRCA2(h) + brca1(h) + BARD1(h) <==> BRCA2(h):brca1(h):BARD1(h) (binding) | RAP80(h) + BARD1(h) <==> RAP80(h):BARD1(h) (binding) | BARD1(h) + brca1(h) <==> BARD1(h):brca1(h) (binding) | Bcl-3(h) + BARD1(h) <==> Bcl-3(h):BARD1(h) (binding) | BARD1(h) + IkappaB-alpha(h) <==> BARD1(h):IkappaB-alpha(h) (binding) | brca1(m) + BARD1(h) <==> brca1(m):BARD1(h) (binding) | BARD1(h) --> BARD1(h) (expression). | BARD1(h) --> BARD1(h) (translocation) |
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Post Transcriptional Modification [Top] | |||
There is no record for BARD1 | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr2 |
Promoter: 215382111 - 215384111 | Agilent_014791 |
chr2 |
Promoter: 215382111 - 215384111 | GSE27584 |
chr2 |
Promoter: 215382111 - 215384111 | Agilent_014791_44K |
chr2 |
Promoter: 215382111 - 215384111 | Agilent_014791 |