| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 5932 |
Name | RBBP8 |
Synonymous | COM1|CTIP|JWDS|RIM|SAE2|SCKL2;retinoblastoma binding protein 8;RBBP8;retinoblastoma binding protein 8 |
Definition | CTBP-interacting protein|DNA endonuclease RBBP8|RBBP-8|sporulation in the absence of SPO11 protein 2 homolog |
Position | 18q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
CtIP(h) + RBTN2(m) <==> CtIP(h):RBTN2(m) (binding) | CtIP(h) + Lmo4(h) <==> CtIP(h):Lmo4(h) (binding) | brca1(h) + CtIP(h) + Lmo4(h) <==> brca1(h):CtIP(h):Lmo4(h) (binding) | CtIP(h) + Lmo4(m) <==> CtIP(h):Lmo4(m) (binding) | huntingtin(h) + CtIP(h) <==> huntingtin(h):CtIP(h) (binding) | CtIP(h) + n ubiquitin(h) --> CtIP(h){ub}n (ubiquitination) | CtIP(h) + n ubiquitin(h) --brca1(m.s.)--> CtIP(h){ub}n (ubiquitination) | CtIP(h) + ATP --> CtIP(h){p} + ADP (phosphorylation) | CtIP(h) + brca1(m.s.) <==> CtIP(h):brca1(m.s.) (binding) | brca1(h) + CtIP(h) <==> brca1(h):CtIP(h) (binding) | CtIP(h) + RAP80(h) <==> CtIP(h):RAP80(h) (binding) | CtIP(h) + RAP80(m.s.) <==> CtIP(h):RAP80(m.s.) (binding) | BARD1(h) + BRCA2(h) + brca1(h) + Bach1(h) + MLH1(h) + tubulin(h) + CtIP(h) <==> BARD1(h):BRCA2(h):brca1(h):Bach1(h):MLH1(h):tubulin(h):CtIP(h) (binding) | Mre11(h) + CtIP(h) + Bach1(h) + Rad50(h) + BARD1(h) <==> Mre11(h):CtIP(h):Bach1(h):Rad50(h):BARD1(h) (binding) | CtIP(h) + Rad50(h) + brca1(h) + BARD1(h) <==> CtIP(h):Rad50(h):brca1(h):BARD1(h) (binding) | Mre11(h) + NBS1(h) + CtIP(h) + Rad50(h) + brca1(h) <==> Mre11(h):NBS1(h):CtIP(h):Rad50(h):brca1(h) (binding) | CtIP(h) + brca1(h) + ZBRK1(h) <==> CtIP(h):brca1(h):ZBRK1(h) (binding) | CtIP(h) + ATP --> CtIP(h){pS327} + ADP (phosphorylation) | CtIP(h) --> Chk1(h){pS317} (increase of phosphorylation) | PINCH-1(h) + CtIP(h) <==> PINCH-1(h):CtIP(h) (binding) | Pin1(h) + CtIP(h) <==> Pin1(h):CtIP(h) (binding) | CtIP(h) + p107(h) <==> CtIP(h):p107(h) (binding) | CtIP(h) + FXR2(h) <==> CtIP(h):FXR2(h) (binding) | CtIP(h) + FLJ10204(h) <==> CtIP(h):FLJ10204(h) (binding) | CtIP(h) + DMC1(h) <==> CtIP(h):DMC1(h) (binding) | RBBP8(h) --> CtIP(h) (expression). | CtIP(h) + n ubiquitin(h) --E1(m.s.),Ubc5C(m.s.),brca1(h):BARD1(h)--> CtIP(h){ub}n (ubiquitination) | CtIP(h) + ATP --ATM(m.s.)--> CtIP(h){pS664} + ADP (phosphorylation) | CtIP(h) + ATP --ATR(m.s.)--> CtIP(h){pS664} + ADP (phosphorylation) | CtIP(h) + ATP --DNA-PK(m.s.)--> CtIP(h){pS664} + ADP (phosphorylation) | RBBP8(h) --> CtIP(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for RBBP8 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr18 |
Promoter: 18765793 - 18767793 | Agilent_014791 |
chr18 |
Promoter: 18766337 - 18768337 | Agilent_014791 |
chr18 |
Promoter: 18766337 - 18768337 | GSE27584 |
chr18 |
Promoter: 18766337 - 18768337 | GSE27584 |
chr18 |
Promoter: 18765793 - 18767793 | GSE27584 |
chr18 |
Promoter: 18765793 - 18767793 | Agilent_014791_44K |
chr18 |
Promoter: 18765793 - 18767793 | Agilent_014791 |
chr18 |
Promoter: 18766337 - 18768337 | Agilent_014791 |