Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

652

Name

BMP4

Synonymous

BMP2B|BMP2B1|MCOPS6|OFC11|ZYME;bone morphogenetic protein 4;BMP4;bone morphogenetic protein 4

Definition

BMP-2B|BMP-4|bone morphogenetic protein 2B

Position

14q22-q23

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for BMP4

Transcription Factors   [Top]

Regulation From TransFac database

BMP4(h) + noggin(h) <==> BMP4(h):noggin(h) (binding)
BMP4(h) --> BMP4(h) (expression).
BMP4(h) --> Smad1(h):Nkx3-2(c) (increase of binding)
BMP4(h) --> HDAC1(m.s.):Nkx3-2(c) (increase of binding)
BMP4(h) --> BMP4(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

143N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
208N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
350N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
365N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr14

Promoter: 53492862 - 53494862Agilent_014791

chr14

Promoter: 53490520 - 53492520Agilent_014791

chr14

Promoter: 53492862 - 53494862GoldenGate_Methylation_Cancer_Panel_I

chr14

Promoter: 53492862 - 53494862GoldenGate_Methylation_Cancer_Panel_I

chr14

Promoter: 53492862 - 53494862GSE27584

chr14

Promoter: 53490520 - 53492520GSE27584

chr14

Promoter: 53492862 - 53494862GSE27584

chr14

Promoter: 53490520 - 53492520Agilent_014791


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