General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 6595 |
Name | SMARCA2 |
Synonymous | BAF190|BRM|NCBRS|SNF2|SNF2L2|SNF2LA|SWI2|Sth1p|hBRM|hSNF2a;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2;SMARCA2;SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
Definition | ATP-dependent helicase SMARCA2|BAF190B|BRG1-associated factor 190B|SNF2-alpha|SNF2/SWI2-like protein 2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2|global transcription activator homologous sequence|probable global transcrip |
Position | 9p22.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
Brm(h) + HDAC1(h) + hdac2(h) + RbAp48(h) + BAF155(h) + BAF60A(h) + sin3a(h) <==> Brm(h):HDAC1(h):hdac2(h):RbAp48(h):BAF155(h):BAF60A(h):sin3a(h) (binding) | sin3a(h) + Brm(h) <==> sin3a(h):Brm(h) (binding) | Brm(h) + ER-alpha(h) <==> Brm(h):ER-alpha(h) (binding) | Brm(h) + ARID1B(h) <==> Brm(h):ARID1B(h) (binding) | Brm(h) + BAF250(h) <==> Brm(h):BAF250(h) (binding) | Brm(h) --> ABCB1(h) (DNA binding; transactivation). | BAF47(h) + BAF155(h) + BAF170(h) + Brm(h) + BRG1(h) + MCPH1(m.s.) <==> BAF47(h):BAF155(h):BAF170(h):Brm(h):BRG1(h):MCPH1(m.s.) (binding) | BRG1(h) + Brm(h) + MCT(h) <==> BRG1(h):Brm(h):MCT(h) (binding) | BAF155(h) + Brm(h) + MCPH1(m.s.) <==> BAF155(h):Brm(h):MCPH1(m.s.) (binding) | BAF47(h) + Brm(h) + BRG1(h) + BAF155(h) + BAF170(h) <==> BAF47(h):Brm(h):BRG1(h):BAF155(h):BAF170(h) (binding) | SMARCA2(h) --> Brm(h) (expression). | SMARCA2(h) --> Brm-L(h) (expression). | SMARCA2(h) --> Brm-S(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
325 | Phosphoserine. | Swiss-Prot 53.0 | 587 | Phosphoserine. | Swiss-Prot 53.0 | 952 | Phosphoserine. | Swiss-Prot 53.0 | 1373 | Phosphoserine. | Swiss-Prot 53.0 | 1414 | Phosphoserine. | Swiss-Prot 53.0 | 1415 | Phosphoserine. | Swiss-Prot 53.0 | 1547 | N6-acetyllysine. | Swiss-Prot 53.0 | 1549 | N6-acetyllysine. | Swiss-Prot 53.0 | 1551 | N6-acetyllysine. | Swiss-Prot 53.0 | 1564 | Phosphoserine. | Swiss-Prot 53.0 | 1568 | Phosphoserine. | Swiss-Prot 53.0 | 587 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 1564 | Phosphoserine | 16097034;17081983 | Phospho.ELM 6.0 | 1568 | Phosphoserine | 16097034;17081983 | Phospho.ELM 6.0 | 322 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 325 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 611 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 1373 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr9 |
Promoter: 2003842 - 2005842 | Agilent_014791 |
chr9 |
Promoter: 2003842 - 2005842 | GSE27584 |
chr9 |
Promoter: 2003842 - 2005842 | GSE27584 |
chr9 |
Promoter: 2003842 - 2005842 | Agilent_014791_44K |
chr9 |
Promoter: 2003842 - 2005842 | Agilent_014791 |