Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6596

Name

HLTF

Synonymous

HIP116|HIP116A|HLTF1|RNF80|SMARCA3|SNF2L3|ZBU1;helicase-like transcription factor;HLTF;helicase-like transcription factor

Definition

DNA-binding protein/plasminogen activator inhibitor 1 regulator|DNA-binding protein/plasminogen activator inhibitor-1 regulator|RING finger protein 80|SNF2-like 3|SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, mem

Position

3q25.1-q26.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ZBU1(h) --> HIV-1(HIV1) (DNA binding).
ZBU1(h) --> SV40(sv) (DNA binding).
ZBU1(h) --> SERPINE1(h) (DNA binding; transactivation).
HLTF(h) --> ZBU1(h) (expression).
HLTF (Met123)(h) --> SERPINE1(h) (DNA binding; transregulation).
HLTF(h) --> HLTF (Met123)(h) (expression).
HLTF(h) --> ZBU1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

397Phosphoserine.Swiss-Prot 53.0
398Phosphoserine.Swiss-Prot 53.0
400Phosphoserine.Swiss-Prot 53.0
635Phosphoserine (By similarity).Swiss-Prot 53.0
398Phosphoserine15302935;17081983Phospho.ELM 6.0
397Phosphoserine17081983Phospho.ELM 6.0
400Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 150286531 - 150288531GoldenGate_Methylation_Cancer_Panel_I

chr3

Promoter: 150286531 - 150288531GoldenGate_Methylation_Cancer_Panel_I

chr3

Promoter: 150286531 - 150288531GSE27584

chr3

Promoter: 150286531 - 150288531GSE27584

chr3

Promoter: 150286531 - 150288531Agilent_014791_44K

chr3

Promoter: 150286531 - 150288531Agilent_014791_44K

chr3

Promoter: 150286531 - 150288531Agilent_014791

chr3

Promoter: 150286531 - 150288531PMID:15386372

chr3

Promoter: 150286531 - 150288531PMID:15386372

chr3

Promoter: 150286531 - 150288531PMID:15760919

chr3

Promoter: 150286531 - 150288531PMID:15760919

chr3

Promoter: 150286531 - 150288531PMID:17189406

chr3

Promoter: 150286531 - 150288531PMID:17189406

chr3

Promoter: 150286531 - 150288531PMID:17378912

chr3

Promoter: 150286531 - 150288531PMID:17378912

chr3

Promoter: 150286531 - 150288531PMID:16475210

chr3

Promoter: 150286531 - 150288531PMID:16475210

chr3

Promoter: 150286531 - 150288531PMID:12766908

chr3

Promoter: 150286531 - 150288531PMID:12766908

chr3

Promoter: 150286531 - 150288531PMID:16497821

chr3

Promoter: 150286531 - 150288531PMID:16497821

chr3

Promoter: 150286531 - 150288531PMID:12901794

chr3

Promoter: 150286531 - 150288531PMID:12901794

chr3

Promoter: 150286531 - 150288531PMID:16331610

chr3

Promoter: 150286531 - 150288531PMID:16331610

chr3

Promoter: 150286531 - 150288531PMID:17139617

chr3

Promoter: 150286531 - 150288531PMID:17139617


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