Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6876

Name

TAGLN

Synonymous

SM22|SMCC|TAGLN1|WS3-10;transgelin;TAGLN;transgelin

Definition

22 kDa actin-binding protein|SM22-alpha|smooth muscle protein 22-alpha|transgelin variant 2

Position

11q23.2

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

SM22(h) + ARA54(m.s.) <==> SM22(h):ARA54(m.s.) (binding)
ARA54(h) + SM22(h) <==> ARA54(h):SM22(h) (binding)
SM22(h) --/ kallikrein-3(h) (decrease of abundance)
SM22(h) + MRP-14(h) <==> SM22(h):MRP-14(h) (binding)
cofilin-1(h) + SM22(h) <==> cofilin-1(h):SM22(h) (binding)
GIPC1(h) + SM22(h) <==> GIPC1(h):SM22(h) (binding)
TAGLN(h) --> SM22(h) (expression).
SM22(h) + ARA54(m.s.) <==> SM22(h):ARA54(m.s.) (binding)
AR-isoform1(h) + SM22(h) <==> AR-isoform1(h):SM22(h) (binding)
SM22(h) --/ KLK3(h) (transrepression)
SM22(h) --/ kallikrein-3(h) (decrease of abundance)
TAGLN(h) --> SM22(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

2N-acetylalanine (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 116573750 - 116575750GSE27584

chr11

Promoter: 116573750 - 116575750GSE27584


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