| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 6925 |
Name | TCF4 |
Synonymous | E2-2|ITF-2|ITF2|PTHS|SEF-2|SEF2|SEF2-1|SEF2-1A|SEF2-1B|SEF2-1D|TCF-4|bHLHb19;transcription factor 4;TCF4;transcription factor 4 |
Definition | SL3-3 enhancer factor 2|class B basic helix-loop-helix protein 19|immunoglobulin transcription factor 2 |
Position | 18q21.1 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
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Regulation From TransFac database |
ITF-2(h) + Id1(m) <==> ITF-2(h):Id1(m) (binding). | ITF-2(h) + ITF-1(h) <==> ITF-2(h):ITF-1(h) (binding). | Tal1-PP42(h) + ITF-2(h) <==> Tal1-PP42(h):ITF-2(h) (binding). | Tal1-PP22(h) + ITF-2(h) <==> Tal1-PP22(h):ITF-2(h) (binding). | ITF-2(h) + MyoD(h) <==> ITF-2(h):MyoD(h) (binding). | ITF-2(h) + MEF1(m) <==> ITF-2(h):MEF1(m) (binding). | ITF-2(h) + Myogenin(h) <==> ITF-2(h):Myogenin(h) (binding). | ITF-2(h) + Myf-5(h) <==> ITF-2(h):Myf-5(h) (binding). | ITF-2(h) + Myf-6(h) <==> ITF-2(h):Myf-6(h) (binding). | ITF-2(h) + MyoD(x) <==> ITF-2(h):MyoD(x) (binding). | ITF-2(h) + MyoD(m) <==> ITF-2(h):MyoD(m) (binding). | ITF-2(h) + MyoD(mo) <==> ITF-2(h):MyoD(mo) (binding). | Myf-5(x) + ITF-2(h) <==> Myf-5(x):ITF-2(h) (binding). | MyoD(c) + ITF-2(h) <==> MyoD(c):ITF-2(h) (binding). | HTF4(h) + ITF-2(h) <==> HTF4(h):ITF-2(h) (binding). | Id1.25(r) + ITF-2(h) <==> Id1.25(r):ITF-2(h) (binding). | Id1(r) + ITF-2(h) <==> Id1(r):ITF-2(h) (binding). | PIAS1(h) + ITF-2(h) <==> PIAS1(h):ITF-2(h) (binding) | ITF-2(h) + PIAS2-beta(h) <==> ITF-2(h):PIAS2-beta(h) (binding) | ITF-2(h) + PIAS1(m) <==> ITF-2(h):PIAS1(m) (binding) | Id2(h) + ITF-2(h) <==> Id2(h):ITF-2(h) (binding) | Id3(h) + ITF-2(h) <==> Id3(h):ITF-2(h) (binding) | ITF-2(h) + msc(h) <==> ITF-2(h):msc(h) (binding) | ITF-2(h) + hbp1(h) <==> ITF-2(h):hbp1(h) (binding) | TCF4(h) --> ITF-2(h) (expression). | SEF2-1B(h) --> CKM(m) (DNA binding). | SEF2-1B(h) --> MLC(r) (DNA binding). | SEF2-1B(h) --> IgH(m) (DNA binding). | SEF2-1B(h) --> AMHR2(h) (DNA binding; transactivation). | TCF4(h) --> SEF2-1B(h) (expression). | TCF4(h) --> SEF2-1A(h) (expression). | TCF4(h) --> SEF2-1D(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
54 | Phosphoserine (CK2 alpha) | 11711551 | Phospho.ELM 6.0 | 55 | Phosphoserine (CK2 alpha) | 11711551 | Phospho.ELM 6.0 | 56 | Phosphoserine (CK2 alpha) | 11711551 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr18 |
Promoter: 51405941 - 51407941 | Agilent_014791 |
chr18 |
Promoter: 51405941 - 51407941 | GoldenGate_Methylation_Cancer_Panel_I |
chr18 |
Promoter: 51405941 - 51407941 | GSE27584 |