| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 7067 |
Name | THRA |
Synonymous | AR7|CHNG6|EAR7|ERB-T-1|ERBA|ERBA1|NR1A1|THRA1|THRA2|c-ERBA-1;thyroid hormone receptor, alpha;THRA;thyroid hormone receptor, alpha |
Definition | EAR-7|ERBA-related 7|V-erbA-related protein 7|c-erbA-alpha|nuclear receptor subfamily 1 group A member 1|thyroid hormone receptor alpha|thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)|thyroid normone nucle |
Position | 17q11.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
T3R-alpha(h) --> GH(r) (DNA binding; transregulation). | T3R-alpha(h) --> Mo-MuLV(MOMLV) (DNA binding; transregulation). | T3R-alpha(h) --> beta-MHC(r) (DNA binding). | T3R-alpha(h) + RAR(mo) <==> T3R-alpha(h):RAR(mo) (binding). | T3R-alpha(h) + RAR(m) <==> T3R-alpha(h):RAR(m) (binding). | T3R-alpha(h) + NR1B1-isoform1(h) <==> T3R-alpha(h):NR1B1-isoform1(h) (binding). | T3R-alpha(h) + RAR-gamma(h) <==> T3R-alpha(h):RAR-gamma(h) (binding). | REVERB-alpha(h) + T3R-alpha(h) <==> REVERB-alpha(h):T3R-alpha(h) (binding). | NCOR1(h) + T3R-alpha(h) <==> NCOR1(h):T3R-alpha(h) (binding) | NCOR1(m) + T3R-alpha(h) <==> NCOR1(m):T3R-alpha(h) (binding). | T3R-alpha(h) + PNRC2(h) <==> T3R-alpha(h):PNRC2(h) (binding) | T3R-alpha(h) + ER-alpha-L(h) <==> T3R-alpha(h):ER-alpha-L(h) (binding) | 14-3-3eta(h) + T3R-alpha(h) <==> 14-3-3eta(h):T3R-alpha(h) (binding) | TIF1a-short(h) + T3R-alpha(h) <==> TIF1a-short(h):T3R-alpha(h) (binding) | T3R-alpha(h) + DAP3(h) <==> T3R-alpha(h):DAP3(h) (binding) | ASC-2(m) + T3R-alpha(h) <==> ASC-2(m):T3R-alpha(h) (binding) | T3R-alpha(h) + RIP140(h) <==> T3R-alpha(h):RIP140(h) (binding) | T3R-alpha(h) + HR-xbb1(r) <==> T3R-alpha(h):HR-xbb1(r) (binding) | T3R-alpha(h) + Cul-1(h) <==> T3R-alpha(h):Cul-1(h) (binding) | T3R-alpha(h) + RGN(h) <==> T3R-alpha(h):RGN(h) (binding) | T3R-alpha(h) + RXR-gamma(h) <==> T3R-alpha(h):RXR-gamma(h) (binding) | T3R-alpha(h) + RXR-beta(h) <==> T3R-alpha(h):RXR-beta(h) (binding) | T3R-alpha(h) + RXR-alpha(h) <==> T3R-alpha(h):RXR-alpha(h) (binding) | T3R-alpha(h) --> Tshb(r) (DNA binding; transactivation). | rT3 + T3R-alpha(h) <==> rT3:T3R-alpha(h) (binding) | T3 + T3R-alpha(h) <==> T3:T3R-alpha(h) (binding) | Triac + T3R-alpha(h) <==> Triac:T3R-alpha(h) (binding) | L-thyroxine + T3R-alpha(h) <==> L-thyroxine:T3R-alpha(h) (binding) | Tetrac + T3R-alpha(h) <==> Tetrac:T3R-alpha(h) (binding) | THRA(h) --> T3R-alpha(h) (expression). | T3R-alpha1(h) --> VIT-A2(x) (DNA binding). | T3R-alpha1(h) + RXR-alpha(h) <==> T3R-alpha1(h):RXR-alpha(h) (binding). | RXR-alpha(m) + T3R-alpha1(h) <==> RXR-alpha(m):T3R-alpha1(h) (binding). | T3R-alpha1(h) + RXR-alpha(x) <==> T3R-alpha1(h):RXR-alpha(x) (binding). | ERK1(h){p} + T3R-alpha1(h) <==> ERK1(h){p}:T3R-alpha1(h) (binding) | ERK2(h){p} + T3R-alpha1(h) <==> ERK2(h){p}:T3R-alpha1(h) (binding) | T3R-alpha1(h) + ATP --ERK2(m){p}--> T3R-alpha1(h){p} + ADP (phosphorylation) | ERK2(mo) + T3R-alpha1(h) <==> ERK2(mo):T3R-alpha1(h) (binding) | SMRT(h) + T3R-alpha1(h) <==> SMRT(h):T3R-alpha1(h) (binding) | T3R-alpha1(h) + TFIIB(h) <==> T3R-alpha1(h):TFIIB(h) (binding). | DRIP205-isoform1(h) + T3R-alpha1(h) <==> DRIP205-isoform1(h):T3R-alpha1(h) (binding) | DRIP205(h) + T3R-alpha1(h) <==> DRIP205(h):T3R-alpha1(h) (binding) | cyclinD1(m.s.) + T3R-alpha1(h) <==> cyclinD1(m.s.):T3R-alpha1(h) (binding) | POU2F1(m.s.) + T3R-alpha1(h) <==> POU2F1(m.s.):T3R-alpha1(h) (binding) | Oct-2(m.s.) + T3R-alpha1(h) <==> Oct-2(m.s.):T3R-alpha1(h) (binding) | RXR-alpha(h) + T3R-alpha1(h) <==> RXR-alpha(h):T3R-alpha1(h) (binding) | ASC-2(h) + T3R-alpha1(h) <==> ASC-2(h):T3R-alpha1(h) (binding) | T3R-alpha1(h) + HR-xbb1(r) <==> HR-xbb1(r):T3R-alpha1(h) (binding) | T3R-alpha1(h) --> Ctnnb1(m) (transactivation) | THRA(h) --> T3R-alpha1(h) (expression). | T3R-alpha2(h) --> TSHB(h) (DNA binding; transregulation). | T3R-alpha2(h) + HR-xbb1(r) <==> T3R-alpha2(h):HR-xbb1(r) (binding) | CRT(m) + T3R-alpha2(h) <==> CRT(m):T3R-alpha2(h) (binding) | THRA(h) --> T3R-alpha2(h) (expression). | THRA(h) --> T3R-alpha3(h) (expression). | THRA(h) --> T3R-alpha4(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for THRA | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr17 |
Promoter: 35471186 - 35473186 | Agilent_014791 |
chr17 |
Promoter: 35471089 - 35473089 | GSE27584 |
chr17 |
Promoter: 35471186 - 35473186 | GSE27584 |
chr17 |
Promoter: 35471186 - 35473186 | Agilent_014791_44K |