Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7159

Name

TP53BP2

Synonymous

53BP2|ASPP2|BBP|P53BP2|PPP1R13A;tumor protein p53 binding protein 2;TP53BP2;tumor protein p53 binding protein 2

Definition

BCL2-binding protein|apoptosis-stimulating of p53 protein 2|apoptosis-stimulating protein of p53, 2|renal carcinoma antigen NY-REN-51|tumor protein p53 binding protein, 2|tumor suppressor p53-binding protein 2

Position

1q41

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ASPP2(h) + p53(h) <==> ASPP2(h):p53(h) (binding)
ASPP2(h) + p63gamma(h) <==> ASPP2(h):p63gamma(h) (binding)
ASPP2(h) + p73alpha(h) <==> ASPP2(h):p73alpha(h) (binding)
Bcl-2(h) + ASPP2(h) <==> Bcl-2(h):ASPP2(h) (binding)
HCV-core-1B(HCV1B) + ASPP2(h) <==> HCV-core-1B(HCV1B):ASPP2(h) (binding)
HCV-core(HCV) + ASPP2(h) <==> HCV-core(HCV):ASPP2(h) (binding)
p53(m.s.) + ASPP2(h) <==> p53(m.s.):ASPP2(h) (binding)
2 ASPP2(h) <==> (ASPP2(h))2 (oligomerization)
ASPP2(h) + EEF1A(h) <==> ASPP2(h):EEF1A(h) (binding)
ASPP2(h) + kif5a(h) <==> ASPP2(h):kif5a(h) (binding)
ASPP2(h) + PTN(h) <==> ASPP2(h):PTN(h) (binding)
ASPP2(h) + RG4(h) <==> ASPP2(h):RG4(h) (binding)
ASPP2(h) + utp14A(h) <==> ASPP2(h):utp14A(h) (binding)
TP53BP2(h) --> ASPP2(h) (expression).
ASPP2-isoform2(h) + IRS-1(r) <==> ASPP2-isoform2(h):IRS-1(r) (binding)
ASPP2-isoform2(h) + IRS-3(r) <==> ASPP2-isoform2(h):IRS-3(r) (binding)
ASPP2-isoform2(h) + IRS-4(h) <==> ASPP2-isoform2(h):IRS-4(h) (binding)
ASPP2-isoform2(h) + IRS-2(m) <==> ASPP2-isoform2(h):IRS-2(m) (binding)
ASPP2-isoform2(h) + IRS-1(m) <==> ASPP2-isoform2(h):IRS-1(m) (binding)
TP53BP2(h) --> ASPP2-isoform2(h) (expression).
ASPP2-isoform1(h) + IRS-1(r) <==> ASPP2-isoform1(h):IRS-1(r) (binding)
TP53BP2(h) --> ASPP2-isoform1(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

480Phosphoserine (By similarity).Swiss-Prot 53.0
698Phosphoserine.Swiss-Prot 53.0
698Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 222099797 - 222101797Agilent_014791

chr1

Promoter: 222099797 - 222101797GSE27584

chr1

Promoter: 222099797 - 222101797GSE27584

chr1

Promoter: 222099797 - 222101797Agilent_014791_44K


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