General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 7159 |
Name | TP53BP2 |
Synonymous | 53BP2|ASPP2|BBP|P53BP2|PPP1R13A;tumor protein p53 binding protein 2;TP53BP2;tumor protein p53 binding protein 2 |
Definition | BCL2-binding protein|apoptosis-stimulating of p53 protein 2|apoptosis-stimulating protein of p53, 2|renal carcinoma antigen NY-REN-51|tumor protein p53 binding protein, 2|tumor suppressor p53-binding protein 2 |
Position | 1q41 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
ASPP2(h) + p53(h) <==> ASPP2(h):p53(h) (binding) | ASPP2(h) + p63gamma(h) <==> ASPP2(h):p63gamma(h) (binding) | ASPP2(h) + p73alpha(h) <==> ASPP2(h):p73alpha(h) (binding) | Bcl-2(h) + ASPP2(h) <==> Bcl-2(h):ASPP2(h) (binding) | HCV-core-1B(HCV1B) + ASPP2(h) <==> HCV-core-1B(HCV1B):ASPP2(h) (binding) | HCV-core(HCV) + ASPP2(h) <==> HCV-core(HCV):ASPP2(h) (binding) | p53(m.s.) + ASPP2(h) <==> p53(m.s.):ASPP2(h) (binding) | 2 ASPP2(h) <==> (ASPP2(h))2 (oligomerization) | ASPP2(h) + EEF1A(h) <==> ASPP2(h):EEF1A(h) (binding) | ASPP2(h) + kif5a(h) <==> ASPP2(h):kif5a(h) (binding) | ASPP2(h) + PTN(h) <==> ASPP2(h):PTN(h) (binding) | ASPP2(h) + RG4(h) <==> ASPP2(h):RG4(h) (binding) | ASPP2(h) + utp14A(h) <==> ASPP2(h):utp14A(h) (binding) | TP53BP2(h) --> ASPP2(h) (expression). | ASPP2-isoform2(h) + IRS-1(r) <==> ASPP2-isoform2(h):IRS-1(r) (binding) | ASPP2-isoform2(h) + IRS-3(r) <==> ASPP2-isoform2(h):IRS-3(r) (binding) | ASPP2-isoform2(h) + IRS-4(h) <==> ASPP2-isoform2(h):IRS-4(h) (binding) | ASPP2-isoform2(h) + IRS-2(m) <==> ASPP2-isoform2(h):IRS-2(m) (binding) | ASPP2-isoform2(h) + IRS-1(m) <==> ASPP2-isoform2(h):IRS-1(m) (binding) | TP53BP2(h) --> ASPP2-isoform2(h) (expression). | ASPP2-isoform1(h) + IRS-1(r) <==> ASPP2-isoform1(h):IRS-1(r) (binding) | TP53BP2(h) --> ASPP2-isoform1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
480 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 698 | Phosphoserine. | Swiss-Prot 53.0 | 698 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
---|---|---|
chr1 |
Promoter: 222099797 - 222101797 | Agilent_014791 |
chr1 |
Promoter: 222099797 - 222101797 | GSE27584 |
chr1 |
Promoter: 222099797 - 222101797 | GSE27584 |
chr1 |
Promoter: 222099797 - 222101797 | Agilent_014791_44K |