Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7182

Name

NR2C2

Synonymous

TAK1|TR4;nuclear receptor subfamily 2, group C, member 2;NR2C2;nuclear receptor subfamily 2, group C, member 2

Definition

Nuclear hormone receptor TR4|nuclear receptor subfamily 2 group C member 2|orphan nuclear receptor TAK1|orphan nuclear receptor TR4|testicular nuclear receptor 4

Position

3p25

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ER-alpha(m.s.) + TR4(h) <==> ER-alpha(m.s.):TR4(h) (binding)
TR4(h) + RXR-beta(h) <==> TR4(h):RXR-beta(h) (binding)
TR4(h) + ATP --> TR4(h){pT178}{pT184} + ADP (phosphorylation)
TR4(h) --> apoE(h) (DNA binding).
TR4(h) --> LHCGR(h) (DNA binding).
NR2C2(h) --> TR4(h) (expression).
TR4(h) --/ CYP21B(h) (DNA binding; transrepression).
TR4(h) --> CNTFR(h) (DNA binding; transregulation).
TR4(h) --> apoE(h) (DNA binding; transactivation).
TR4(h) --> LHCGR(h) (DNA binding; transactivation).
2 TR4(h) <==> (TR4(h))2 (binding)
RIP140(m.s.) + TR4(h) <==> RIP140(m.s.):TR4(h) (binding)
TR4(h) --> Rarb(m) (DNA binding).
TR4(h) --> BCL2(h) (DNA binding; transactivation).
NR2C2(h) --> TR4(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for NR2C2

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 14962740 - 14964740Agilent_014791

chr3

Promoter: 14962740 - 14964740GSE27584


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