General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
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Gene ID | 7184 |
Name | HSP90B1 |
Synonymous | ECGP|GP96|GRP94|HEL-S-125m|HEL35|TRA1;heat shock protein 90kDa beta (Grp94), member 1;HSP90B1;heat shock protein 90kDa beta (Grp94), member 1 |
Definition | 94 kDa glucose-regulated protein|endoplasmin|endothelial cell (HBMEC) glycoprotein|epididymis luminal protein 35|epididymis secretory sperm binding protein Li 125m|heat shock protein 90 kDa beta member 1|stress-inducible tumor rejection antigen gp96|tumor |
Position | 12q24.2-q24.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
Grp94(h) + AIMP1(m.s.) <==> Grp94(h):AIMP1(m.s.) (binding) | Grp94(h) + Grp94(m.s.) <==> Grp94(h):Grp94(m.s.) (binding; oligomerization) | HSP90B1(h) --> Grp94(h) (expression). | Grp94(h) + AR(h) <==> Grp94(h):AR(h) (binding) | ErbB2(h) + Grp94(h) <==> ErbB2(h):Grp94(h) (binding) | Grp94(h) + AIMP1(h) <==> Grp94(h):AIMP1(h) (binding) | Grp94(h) + AIMP1(m.s.) <==> Grp94(h):AIMP1(m.s.) (binding) | HSP90B1(h) --> Grp94(h) (expression). | HCV-core-1B(HCV1B) --> Grp94(h) (increase of abundance) |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
62 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 107 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 217 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 445 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 481 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 502 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
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chr12 |
Promoter: 102846819 - 102848819 | GSE27584 |
chr12 |
Promoter: 102846819 - 102848819 | Agilent_014791_44K |