Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7403

Name

KDM6A

Synonymous

KABUK2|UTX|bA386N14.2;lysine (K)-specific demethylase 6A;KDM6A;lysine (K)-specific demethylase 6A

Definition

bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX))|histone demethylase UTX|lysine-specific demethylase 6A|ubiquitously transcribed tetratricopeptide repeat protein X-linked|ubiquitously-transcribed TPR gene on the X

Position

Xp11.2

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for KDM6A

Transcription Factors   [Top]

Regulation From TransFac database

UTX(h) --> histone H3(mo){metK28} (decrease of methylation)
UTX(h) --> histone H3(mo){met(2)K28} (decrease of methylation)
UTX(h) --> histone H3(mo){met(3)K28} (decrease of methylation)
UTX(h) --> UTX(h) (expression).
histone H3(b){metK28} --UTX(h)--> histone H3(b) + formaldehyde (demethylation)
histone H3(b){met(2)K28} --UTX(h)--> histone H3(b) + 2 formaldehyde (demethylation)
histone H3(b){met(3)K28} --UTX(h)--> histone H3(b) + 3 formaldehyde (demethylation)
UTX(h) --> UTX(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for KDM6A

Methylation Profile   [Top]

Chromosome

Location

Source

chrX

Promoter: 44616225 - 44618225GSE27584

chrX

Promoter: 44616225 - 44618225Agilent_014791_44K


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