Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7791

Name

ZYX

Synonymous

ESP-2|HED-2;zyxin;ZYX;zyxin

Definition

zyxin-2

Position

7q32

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

zyxin(h) + ATP --cyclinB1(h):Cdk1(h)--> zyxin(h){p} + ADP (phosphorylation)
zyxin(h) + CIZ(h) <==> zyxin(h):CIZ(h) (binding)
IEX1(h) + zyxin(h) <==> IEX1(h):zyxin(h) (binding)
ZYX(h) --> zyxin(h) (expression).
zyxin(h) + CIZ(h) <==> zyxin(h):CIZ(h) (binding)
zyxin(h) + Cas(h) + CIZ(h) <==> zyxin(h):Cas(h):CIZ(h) (binding)
ZYX(h) --> zyxin(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

259Phosphoserine.Swiss-Prot 53.0
267Phosphoserine.Swiss-Prot 53.0
281Phosphoserine.Swiss-Prot 53.0
290Phosphoserine.Swiss-Prot 53.0
344Phosphoserine.Swiss-Prot 53.0
259Phosphoserine15302935Phospho.ELM 6.0
267Phosphoserine15302935Phospho.ELM 6.0
344Phosphoserine15302935;17081983Phospho.ELM 6.0
303Phosphoserine17081983Phospho.ELM 6.0
308Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 142786982 - 142788982Agilent_014791

chr7

Promoter: 142786982 - 142788982GSE27584

chr7

Promoter: 142786982 - 142788982GSE27584

chr7

Promoter: 142786982 - 142788982Agilent_014791_44K


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