Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7799

Name

PRDM2

Synonymous

HUMHOXY1|KMT8|MTB-ZF|RIZ|RIZ1|RIZ2;PR domain containing 2, with ZNF domain;PRDM2;PR domain containing 2, with ZNF domain

Definition

GATA-3 binding protein G3B|GATA-3-binding protein G3B|MTE-binding protein|PR domain zinc finger protein 2|PR domain-containing protein 2|lysine N-methyltransferase 8|retinoblastoma protein-binding zinc finger protein|retinoblastoma protein-interacting zin

Position

1p36.21

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

pRb(h) + MTB-Zf(h) <==> pRb(h):MTB-Zf(h) (binding)
ER-alpha(h) + pRb(h) + MTB-Zf(h) <==> ER-alpha(h):pRb(h):MTB-Zf(h) (binding)
MTB-Zf(h) --> MTB-Zf(h) (translocation)
Prdm2(h) --> MTB-Zf(h) (expression).
MTB-Zf(h) --> MTB-Zf(h) (translocation)
MTB-Zf(h) --> HMOX1(h) (DNA binding).
Prdm2(h) --> MTB-Zf(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

641Phosphothreonine.Swiss-Prot 53.0
643Phosphoserine.Swiss-Prot 53.0
643Phosphoserine15302935;17081983Phospho.ELM 6.0
641Phosphothreonine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 13946963 - 13948963Agilent_014791

chr1

Promoter: 13902437 - 13904437Agilent_014791

chr1

Promoter: 13902437 - 13904437GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 13902437 - 13904437GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 13946963 - 13948963GSE27584

chr1

Promoter: 13946963 - 13948963PMID:15897561

chr1

Promoter: 13902437 - 13904437PMID:15897561

chr1

Promoter: 13902437 - 13904437PMID:15897561

chr1

Promoter: 13946963 - 13948963PMID:11719434

chr1

Promoter: 13902437 - 13904437PMID:11719434

chr1

Promoter: 13902437 - 13904437PMID:11719434

chr1

Promoter: 13946963 - 13948963PMID:17177027

chr1

Promoter: 13902437 - 13904437PMID:17177027

chr1

Promoter: 13902437 - 13904437PMID:17177027

chr1

Promoter: 13946963 - 13948963PMID:16888795

chr1

Promoter: 13902437 - 13904437PMID:16888795

chr1

Promoter: 13902437 - 13904437PMID:16888795

chr1

Promoter: 13946963 - 13948963PMID:15069684

chr1

Promoter: 13902437 - 13904437PMID:15069684

chr1

Promoter: 13902437 - 13904437PMID:15069684

chr1

Promoter: 13946963 - 13948963PMID:17052263

chr1

Promoter: 13902437 - 13904437PMID:17052263

chr1

Promoter: 13902437 - 13904437PMID:17052263

chr1

Promoter: 13946963 - 13948963PMID:17103461

chr1

Promoter: 13902437 - 13904437PMID:17103461

chr1

Promoter: 13902437 - 13904437PMID:17103461

chr1

Promoter: 13946963 - 13948963PMID:15316056

chr1

Promoter: 13902437 - 13904437PMID:15316056

chr1

Promoter: 13902437 - 13904437PMID:15316056

chr1

Promoter: 13946963 - 13948963PMID:12631603

chr1

Promoter: 13902437 - 13904437PMID:12631603

chr1

Promoter: 13902437 - 13904437PMID:12631603

chr1

Promoter: 13946963 - 13948963PMID:15447999

chr1

Promoter: 13902437 - 13904437PMID:15447999

chr1

Promoter: 13902437 - 13904437PMID:15447999


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