Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7879

Name

RAB7A

Synonymous

PRO2706|RAB7;RAB7A, member RAS oncogene family;RAB7A;RAB7A, member RAS oncogene family

Definition

RAB7, member RAS oncogene family|Ras-associated protein RAB7|ras-related protein Rab-7a

Position

3q21.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

CXCR2(h) + Rab7(h) <==> CXCR2(h):Rab7(h) (binding)
eIF1b(h) + Rab7(h) <==> eIF1b(h):Rab7(h) (binding)
VHL(h) + Rab7(h) <==> VHL(h):Rab7(h) (binding)
Rab7(h) --> PMEL17-p32(h) (increase of abundance)
Rab7(h) --> PMEL17-p29(h) (increase of abundance)
Rab7(h) --> Rab7(h) (expression).
Rab7(h) --> Rab7(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

183Phosphotyrosine.Swiss-Prot 53.0
205S-geranylgeranyl cysteine (Bysimilarity).Swiss-Prot 53.0
207S-geranylgeranyl cysteine (Bysimilarity).Swiss-Prot 53.0
183Phosphotyrosine15592455Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 129926169 - 129928169GSE27584

chr3

Promoter: 129926169 - 129928169Agilent_014791_44K


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