| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 84152 |
Name | PPP1R1B |
Synonymous | DARPP-32|DARPP32;protein phosphatase 1, regulatory (inhibitor) subunit 1B;PPP1R1B;protein phosphatase 1, regulatory (inhibitor) subunit 1B |
Definition | dopamine and cAMP-regulated neuronal phosphoprotein 32|protein phosphatase 1 regulatory subunit 1B |
Position | 17q12 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
There is no record for PPP1R1B | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
PPP1R1B(h) --> DARPP32-isoform1(h) (expression). | DARPP32(h) + ATP --> DARPP32(h){pT34} + ADP (phosphorylation) | PPP1R1B(h) --> DARPP32(h) (expression). | PPP1R1B(h) --> DARPP32-isoform2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
1 | N-acetylmethionine (By similarity). | Swiss-Prot 53.0 | 34 | Phosphothreonine (by PKA) (Bysimilarity). | Swiss-Prot 53.0 | 75 | Phosphothreonine (by CDK5). | Swiss-Prot 53.0 | 198 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr17 |
Promoter: 35035205 - 35037205 | Agilent_014791 |
chr17 |
Promoter: 35036779 - 35038779 | Agilent_014791 |
chr17 |
Promoter: 35035205 - 35037205 | IlluminaMethylation27 |
chr17 |
Promoter: 35036779 - 35038779 | GSE27584 |
chr17 |
Promoter: 35035205 - 35037205 | GSE27584 |