Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8434

Name

RECK

Synonymous

ST15;reversion-inducing-cysteine-rich protein with kazal motifs;RECK;reversion-inducing-cysteine-rich protein with kazal motifs

Definition

membrane-anchored glycoprotein (metastasis and invasion)|reversion-inducing cysteine-rich protein with Kazal motifs|suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs)|suppression of tumorigenicity 5 (reversion-in

Position

9p13.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

RECK(h) --> RECK(h) (expression).
TIMP-2(h) --> RECK(h) (increase of abundance)
RECK(h) --> RECK(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

39N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
86N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
200N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
297N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
352N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
942GPI-anchor amidated serine (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr9

Promoter: 36025416 - 36027416Agilent_014791

chr9

Promoter: 36025416 - 36027416GSE27584

chr9

Promoter: 36025416 - 36027416Agilent_014791_44K

chr9

Promoter: 36025416 - 36027416PMID:17233834

chr9

Promoter: 36025416 - 36027416PMID:17176274


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