| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 84446 |
Name | BRSK1 |
Synonymous | hSAD1;BR serine/threonine kinase 1;BRSK1;BR serine/threonine kinase 1 |
Definition | BR serine/threonine-protein kinase 1|SAD1 homolog|SAD1 kinase|SadB kinase short isoform|brain-selective kinase 1|brain-specific serine/threonine-protein kinase 1|protein kinase SAD1A|serine/threonine-protein kinase BRSK1|serine/threonine-protein kinase SA |
Position | 19q13.4 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
BRSK1(h) + ATP --LKB1(m):STRADalpha(h):MO25(h)--> BRSK1(h){pT189} + ADP (phosphorylation) | BRSK1(h) + ATP --LKB1(m):STRADalpha(h):MO25beta(h)--> BRSK1(h){pT189} + ADP (phosphorylation) | BRSK1(h) + ATP --LKB1(m):STRADbeta(h):MO25(h)--> BRSK1(h){pT189} + ADP (phosphorylation) | KIAA1811(h) --> BRSK1(h) (expression). | Hsp70-1(h) + BRSK1(h) <==> Hsp70-1(h):BRSK1(h) (binding) | KIAA1811(h) --> BRSK1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
205 | Phosphothreonine. | Swiss-Prot 53.0 | 209 | Phosphoserine (By similarity). | Swiss-Prot 53.0 | 205 | Phosphothreonine (LKB1) | 14976552 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr19 |
Promoter: 60485846 - 60487846 | GSE27584 |
chr19 |
Promoter: 60485846 - 60487846 | Agilent_014791_44K |