Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8678

Name

BECN1

Synonymous

ATG6|VPS30|beclin1;beclin 1, autophagy related;BECN1;beclin 1, autophagy related

Definition

ATG6 autophagy related 6 homolog|beclin 1 (coiled-coil, moesin-like BCL2 interacting protein)|beclin 1 (coiled-coil, moesin-like BCL2-interacting protein)|beclin-1|coiled-coil myosin-like BCL2-interacting protein

Position

17q21

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Bcl-2(h) + Beclin-1(h) <==> Bcl-2(h):Beclin-1(h) (binding)
Beclin-1(h) + Bcl-X(h) <==> Beclin-1(h):Bcl-X(h) (binding)
Mcl-1(m.s.) + Beclin-1(h) <==> Mcl-1(m.s.):Beclin-1(h) (binding)
Bcl-w(m.s.) + Beclin-1(h) <==> Bcl-w(m.s.):Beclin-1(h) (binding)
Bcl-2(mo) + Beclin-1(h) <==> Bcl-2(mo):Beclin-1(h) (binding)
Beclin-1(h) + WDR94(h) <==> Beclin-1(h):WDR94(h) (binding)
VPS34(h) + Beclin-1(h) + WDR94(h) <==> VPS34(h):Beclin-1(h):WDR94(h) (binding)
VPS34(h) + Beclin-1(h) <==> VPS34(h):Beclin-1(h) (binding)
Beclin-1(h) + VMP1(m.s.) <==> Beclin-1(h):VMP1(m.s.) (binding)
Beclin-1(h) + ER-alpha(h) <==> Beclin-1(h):ER-alpha(h) (binding)
BECN1(h) --> Beclin-1(h) (expression).
Beclin-1(h) + Bcl-2(h) <==> Beclin-1(h):Bcl-2(h) (binding)
Beclin-1(h) + ATG14L(h) <==> Beclin-1(h):ATG14L(h) (binding)
Beclin-1(h) + DHTX(h) <==> Beclin-1(h):DHTX(h) (binding)
Beclin-1(h) + VPS34(h) <==> Beclin-1(h):VPS34(h) (binding)
DHTX(h) + Beclin-1(h) <==> DHTX(h):Beclin-1(h) (binding)
VMP1(h) + Beclin-1(h) <==> VMP1(h):Beclin-1(h) (binding)
BECN1(h) --> Beclin-1(h) (expression).
IkappaB-alpha(h) --/ Beclin-1(h) (decrease of abundance)
RelA-p65(h) --> Beclin-1(h) (increase of abundance)

Post Transcriptional Modification   [Top]

There is no record for BECN1

Methylation Profile   [Top]

There is no record for BECN1



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