| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 9046 |
Name | DOK2 |
Synonymous | p56DOK|p56dok-2;docking protein 2, 56kDa;DOK2;docking protein 2, 56kDa |
Definition | docking protein 2|docking protein 2, 56kD|downstream of tyrosine kinase 2|p56(dok-2) |
Position | 8p21.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
psmd10(h) + p56Dok-2(h) <==> psmd10(h):p56Dok-2(h) (binding) | SSSCA1(h) + p56Dok-2(h) <==> SSSCA1(h):p56Dok-2(h) (binding) | p56Dok-2(h) + APG1(h) <==> p56Dok-2(h):APG1(h) (binding) | p56Dok-2(h) + rab10(h) <==> p56Dok-2(h):rab10(h) (binding) | CIA-II(h) + p56Dok-2(h) <==> CIA-II(h):p56Dok-2(h) (binding) | SPOP(h) + p56Dok-2(h) <==> SPOP(h):p56Dok-2(h) (binding) | p56Dok-2(h) + DNAJB11(h) <==> p56Dok-2(h):DNAJB11(h) (binding) | c-FLIP(h) + p56Dok-2(h) <==> c-FLIP(h):p56Dok-2(h) (binding) | p56Dok-2(h) + KBP(h) <==> p56Dok-2(h):KBP(h) (binding) | p56Dok-2(h) + ATP --> p56Dok-2(h){pY} + ADP (phosphorylation) | LAT(h) + p56Dok-2(h) + SHIP(h) + Grb-2(h) <==> LAT(h):p56Dok-2(h):SHIP(h):Grb-2(h) (binding) | p56Dok-2(h) + ATP --> p56Dok-2(h){pY345} + ADP (phosphorylation) | p56Dok-2(h) + SHIP(h){pY} <==> p56Dok-2(h):SHIP(h){pY} (binding) | SHIP(h){pY} + p56Dok-2(h) + p62Dok-1(h) <==> SHIP(h){pY}:p56Dok-2(h):p62Dok-1(h) (binding) | DOK2(h) --> p56Dok-2(h) (expression). | ErbB1-p170(h) + p56Dok-2(h) <==> p56Dok-2(h):ErbB1-p170(h) (binding) | DOK2(h) --> p56Dok-2(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
271 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 | 299 | Phosphotyrosine. | Swiss-Prot 53.0 | 345 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 | 271 | Phosphotyrosine | 10508618 | Phospho.ELM 6.0 | 299 | Phosphotyrosine | 10508618;12522270;15144186;15592455;16094384 | Phospho.ELM 6.0 | 345 | Phosphotyrosine | 11689432;9764820 | Phospho.ELM 6.0 | 139 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
There is no record for DOK2 | ||