Entrez Gene

Basic Information
Gene ID	9314
Name	KLF4
Synonymous	EZF\|GKLF;Kruppel-like factor 4 (gut);KLF4;Kruppel-like factor 4 (gut)
Definition	Krueppel-like factor 4\|endothelial Kruppel-like zinc finger protein\|epithelial zinc finger protein EZF\|gut-enriched krueppel-like factor
Position	9q31
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
GKLF-isoform1(h) + p53(h) <==> p53(h):GKLF-isoform1(h) (binding)
GKLF-isoform1(h) --/ HBB(h) (DNA binding; transrepression).
GKLF-isoform1(h) --> CDKN1A(h) (DNA binding; transactivation).
GKLF-isoform1(h) --/ Hbb-b1(m) (DNA binding; transrepression).
KLF4(h) --> GKLF-isoform1(h) (expression).
KLF4(h) --> GKLF(h) (expression).
hsa-miR-7 --/ GKLF(h) (predicted)
HDAC1(h) + GKLFa(h) <==> HDAC1(h):GKLFa(h) (binding)
hdac2(h) + GKLFa(h) <==> hdac2(h):GKLFa(h) (binding)
GKLFa(h) --/ ITGAD(h) (DNA binding; transrepression).
KLF4(h) --> GKLFa(h) (expression).
HDAC1(h) + GKLF(h) <==> HDAC1(h):GKLF(h) (binding)
hdac2(h) + GKLF(h) <==> hdac2(h):GKLF(h) (binding)
GKLF(h) --> ITGAD(h) (DNA binding).
GKLF(h) --> SLC5A6(h) (DNA binding).
GKLF(h) + acetyl-CoA --> GKLF(h){aceK} + CoA (acetylation)
GKLF(h) --/ ENG(h) (transrepression)
GKLF(h) --/ ODC1(h) (transrepression)
GKLF(h) --> LAMA3(h) (transactivation)
GKLF(h) --> Odc1(m) (DNA binding; transactivation).
GKLF(h) --> GHRL(h) (DNA binding).
KLF4(h) --> GKLF(h) (expression).
KLF4(h) --> GKLF-isoform2(h) (expression).

Post Transcriptional Modification [Top]
	There is no record for KLF4