| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 9318 |
Name | COPS2 |
Synonymous | ALIEN|CSN2|SGN2|TRIP15;COP9 signalosome subunit 2;COPS2;COP9 signalosome subunit 2 |
Definition | COP9 constitutive photomorphogenic homolog subunit 2|COP9 signalosome complex subunit 2|JAB1-containing signalosome subunit 2|TR-interacting protein 15|TRIP-15|alien homolog|signalosome subunit 2|thyroid receptor interacting protein 15|thyroid receptor-in |
Position | 15q21.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
sin3a(h) + COPS2(h) <==> sin3a(h):COPS2(h) (binding) | T3R-beta1(r) + COPS2(h) <==> T3R-beta1(r):COPS2(h) (binding) | RXR-alpha(h) + COPS2(h) <==> RXR-alpha(h):COPS2(h) (binding) | wdr8(h) + COPS2(h) <==> wdr8(h):COPS2(h) (binding) | COPS2(h) --> HIF-1alpha(h) (increase of abundance) | COPS2(h) --> HIF2A(h) (increase of abundance) | COPS2(h) --> HIF-1alpha(h):VHL(m.s.) (decrease of binding) | COPS2(h) --> COPS2(h) (expression). | COPS2-isoform1(h) + CUL4A-isoform2(h) <==> COPS2-isoform1(h):CUL4A-isoform2(h) (binding) | COPS2-isoform1(h) + DDB1(h) <==> COPS2-isoform1(h):DDB1(h) (binding) | COPS2-isoform1(h) + DDB1(h):CUL4A-isoform2(h) <==> COPS2-isoform1(h):DDB1(h):CUL4A-isoform2(h) (binding) | COPS2(h) --> COPS2-isoform1(h) (expression). | T3R-alpha(r) + Alien(h) <==> T3R-alpha(r):Alien(h) (binding) | T3R-beta(h) + Alien(h) <==> T3R-beta(h):Alien(h) (binding) | Alien(h) + COUP-TF1(h) <==> Alien(h):COUP-TF1(h) (binding) | Alien(h) + sin3a(m) <==> Alien(h):sin3a(m) (binding) | Alien(h) + T3R(m.s.) <==> Alien(h):T3R(m.s.) (binding) | VDR(h) + Alien(h) <==> VDR(h):Alien(h) (binding) | T3R-alpha(c) + Alien(h) <==> T3R-alpha(c):Alien(h) (binding) | Alien(h) --/ Nppa(r) (transrepression) | COPS2(h) --> Alien(h) (expression). | VDR(h):Alien(h) <==> VDR(h) + Alien(h) (dissociation) | T3R-alpha(c):Alien(h) <==> T3R-alpha(c) + Alien(h) (dissociation) | COPS2(h) --> COPS2-isoform2(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
There is no record for COPS2 | |||
Methylation Profile [Top] | ||
There is no record for COPS2 | ||